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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
GTF3C5
All Species:
21.52
Human Site:
Y182
Identified Species:
43.03
UniProt:
Q9Y5Q8
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.18
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9Y5Q8
NP_001116295.1
519
59571
Y182
R
L
D
A
P
V
D
Y
F
Y
R
P
E
T
Q
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001103027
528
60386
Y191
R
L
D
A
P
V
D
Y
F
Y
R
P
E
T
Q
Dog
Lupus familis
XP_537807
520
59982
Y186
R
L
D
T
P
V
D
Y
F
Y
R
P
E
T
Q
Cat
Felis silvestris
Mouse
Mus musculus
Q8R2T8
520
60483
Y182
R
L
D
T
P
V
D
Y
F
Y
R
P
E
T
Q
Rat
Rattus norvegicus
NP_001073410
515
59893
Y182
R
L
D
T
P
V
D
Y
F
Y
R
P
E
T
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511625
516
59384
Y184
R
L
D
T
P
V
D
Y
F
Y
R
P
E
T
Q
Chicken
Gallus gallus
NP_001025855
324
36635
R22
L
E
L
P
S
T
P
R
L
V
C
V
E
Y
P
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_693575
529
60525
F201
L
D
M
P
V
D
Y
F
Y
R
P
D
V
M
H
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_609947
480
55616
G173
H
V
D
T
V
Y
A
G
T
Y
R
I
D
P
S
Honey Bee
Apis mellifera
XP_001122915
497
58075
K194
K
F
T
K
D
P
K
K
L
E
C
I
Y
D
K
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
XP_002309715
515
59755
L171
D
V
P
E
N
I
V
L
R
P
P
S
T
S
S
Maize
Zea mays
NP_001131401
555
62739
H201
N
A
I
S
K
T
M
H
R
G
V
V
Q
E
R
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
97.3
87.3
N.A.
85.1
83.8
N.A.
82.6
45.6
N.A.
53.5
N.A.
27.9
31.6
N.A.
N.A.
Protein Similarity:
100
N.A.
97.7
93.8
N.A.
92.3
90.7
N.A.
90.5
53.9
N.A.
73.1
N.A.
48.3
48.7
N.A.
N.A.
P-Site Identity:
100
N.A.
100
93.3
N.A.
93.3
93.3
N.A.
93.3
6.6
N.A.
0
N.A.
20
0
N.A.
N.A.
P-Site Similarity:
100
N.A.
100
93.3
N.A.
93.3
93.3
N.A.
93.3
6.6
N.A.
13.3
N.A.
33.3
13.3
N.A.
N.A.
Percent
Protein Identity:
23.1
24.8
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
44.8
43.2
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
0
0
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
20
26.6
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
9
0
17
0
0
9
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
17
0
0
0
0
% C
% Asp:
9
9
59
0
9
9
50
0
0
0
0
9
9
9
0
% D
% Glu:
0
9
0
9
0
0
0
0
0
9
0
0
59
9
0
% E
% Phe:
0
9
0
0
0
0
0
9
50
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
9
0
9
0
0
0
0
0
% G
% His:
9
0
0
0
0
0
0
9
0
0
0
0
0
0
9
% H
% Ile:
0
0
9
0
0
9
0
0
0
0
0
17
0
0
0
% I
% Lys:
9
0
0
9
9
0
9
9
0
0
0
0
0
0
9
% K
% Leu:
17
50
9
0
0
0
0
9
17
0
0
0
0
0
0
% L
% Met:
0
0
9
0
0
0
9
0
0
0
0
0
0
9
0
% M
% Asn:
9
0
0
0
9
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
9
17
50
9
9
0
0
9
17
50
0
9
9
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
9
0
50
% Q
% Arg:
50
0
0
0
0
0
0
9
17
9
59
0
0
0
9
% R
% Ser:
0
0
0
9
9
0
0
0
0
0
0
9
0
9
17
% S
% Thr:
0
0
9
42
0
17
0
0
9
0
0
0
9
50
0
% T
% Val:
0
17
0
0
17
50
9
0
0
9
9
17
9
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
9
9
50
9
59
0
0
9
9
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _