KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
GTF3C5
All Species:
33.33
Human Site:
Y305
Identified Species:
66.67
UniProt:
Q9Y5Q8
Number Species:
11
Phosphosite Substitution
Charge Score:
0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9Y5Q8
NP_001116295.1
519
59571
Y305
S
L
W
I
R
F
G
Y
D
P
R
K
N
P
D
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001103027
528
60386
Y314
S
L
W
I
R
F
G
Y
D
P
R
K
N
P
D
Dog
Lupus familis
XP_537807
520
59982
Y309
S
L
W
I
R
Y
G
Y
D
P
R
K
N
P
G
Cat
Felis silvestris
Mouse
Mus musculus
Q8R2T8
520
60483
Y305
S
L
W
I
R
F
G
Y
D
P
R
K
H
P
D
Rat
Rattus norvegicus
NP_001073410
515
59893
Y305
S
L
W
I
R
F
G
Y
D
P
R
K
H
P
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511625
516
59384
Y307
S
L
W
V
R
F
G
Y
D
P
R
K
N
P
E
Chicken
Gallus gallus
NP_001025855
324
36635
Q124
F
Q
G
M
S
D
F
Q
Y
L
A
M
H
S
G
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_693575
529
60525
Y324
S
L
W
V
R
F
G
Y
D
P
R
K
I
P
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_609947
480
55616
L280
S
N
G
P
W
R
T
L
Y
V
R
F
G
Y
D
Honey Bee
Apis mellifera
XP_001122915
497
58075
E296
E
Q
I
R
Q
I
F
E
E
R
P
I
W
S
K
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
XP_002309715
515
59755
Y278
K
F
W
I
R
K
G
Y
D
P
R
K
D
P
D
Maize
Zea mays
NP_001131401
555
62739
Y305
K
F
W
I
R
R
G
Y
D
P
R
K
D
S
E
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
97.3
87.3
N.A.
85.1
83.8
N.A.
82.6
45.6
N.A.
53.5
N.A.
27.9
31.6
N.A.
N.A.
Protein Similarity:
100
N.A.
97.7
93.8
N.A.
92.3
90.7
N.A.
90.5
53.9
N.A.
73.1
N.A.
48.3
48.7
N.A.
N.A.
P-Site Identity:
100
N.A.
100
86.6
N.A.
93.3
93.3
N.A.
86.6
0
N.A.
80
N.A.
20
0
N.A.
N.A.
P-Site Similarity:
100
N.A.
100
93.3
N.A.
100
100
N.A.
100
13.3
N.A.
86.6
N.A.
20
13.3
N.A.
N.A.
Percent
Protein Identity:
23.1
24.8
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
44.8
43.2
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
73.3
60
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
80
73.3
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
9
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
9
0
0
75
0
0
0
17
0
50
% D
% Glu:
9
0
0
0
0
0
0
9
9
0
0
0
0
0
17
% E
% Phe:
9
17
0
0
0
50
17
0
0
0
0
9
0
0
0
% F
% Gly:
0
0
17
0
0
0
75
0
0
0
0
0
9
0
25
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
25
0
0
% H
% Ile:
0
0
9
59
0
9
0
0
0
0
0
9
9
0
0
% I
% Lys:
17
0
0
0
0
9
0
0
0
0
0
75
0
0
9
% K
% Leu:
0
59
0
0
0
0
0
9
0
9
0
0
0
0
0
% L
% Met:
0
0
0
9
0
0
0
0
0
0
0
9
0
0
0
% M
% Asn:
0
9
0
0
0
0
0
0
0
0
0
0
34
0
0
% N
% Pro:
0
0
0
9
0
0
0
0
0
75
9
0
0
67
0
% P
% Gln:
0
17
0
0
9
0
0
9
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
9
75
17
0
0
0
9
84
0
0
0
0
% R
% Ser:
67
0
0
0
9
0
0
0
0
0
0
0
0
25
0
% S
% Thr:
0
0
0
0
0
0
9
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
17
0
0
0
0
0
9
0
0
0
0
0
% V
% Trp:
0
0
75
0
9
0
0
0
0
0
0
0
9
0
0
% W
% Tyr:
0
0
0
0
0
9
0
75
17
0
0
0
0
9
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _