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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
GTF3C5
All Species:
26.36
Human Site:
Y345
Identified Species:
52.73
UniProt:
Q9Y5Q8
Number Species:
11
Phosphosite Substitution
Charge Score:
0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9Y5Q8
NP_001116295.1
519
59571
Y345
V
K
A
K
R
S
T
Y
N
Y
S
L
P
I
T
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001103027
528
60386
Y354
V
K
A
K
R
S
T
Y
N
Y
S
L
P
I
T
Dog
Lupus familis
XP_537807
520
59982
Y349
V
K
A
K
R
S
T
Y
N
Y
S
L
P
I
T
Cat
Felis silvestris
Mouse
Mus musculus
Q8R2T8
520
60483
Y345
V
K
A
K
R
S
T
Y
N
Y
S
L
P
I
T
Rat
Rattus norvegicus
NP_001073410
515
59893
Y345
V
K
A
K
R
S
T
Y
N
Y
S
L
P
I
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511625
516
59384
Y347
V
K
A
K
R
S
T
Y
N
Y
S
L
P
I
T
Chicken
Gallus gallus
NP_001025855
324
36635
P164
E
L
P
L
Y
I
P
P
P
I
F
S
R
L
D
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_693575
529
60525
Y364
V
K
S
K
R
S
A
Y
H
Y
S
R
P
T
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_609947
480
55616
V320
F
V
Y
A
K
K
F
V
K
Q
R
R
A
A
N
Honey Bee
Apis mellifera
XP_001122915
497
58075
L336
V
N
G
P
W
K
I
L
W
V
K
L
G
Y
D
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
XP_002309715
515
59755
D318
G
L
K
H
R
W
E
D
L
C
K
F
R
F
F
Maize
Zea mays
NP_001131401
555
62739
C345
S
R
K
W
A
D
M
C
K
L
E
T
M
P
S
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
97.3
87.3
N.A.
85.1
83.8
N.A.
82.6
45.6
N.A.
53.5
N.A.
27.9
31.6
N.A.
N.A.
Protein Similarity:
100
N.A.
97.7
93.8
N.A.
92.3
90.7
N.A.
90.5
53.9
N.A.
73.1
N.A.
48.3
48.7
N.A.
N.A.
P-Site Identity:
100
N.A.
100
100
N.A.
100
100
N.A.
100
0
N.A.
66.6
N.A.
0
13.3
N.A.
N.A.
P-Site Similarity:
100
N.A.
100
100
N.A.
100
100
N.A.
100
6.6
N.A.
80
N.A.
6.6
13.3
N.A.
N.A.
Percent
Protein Identity:
23.1
24.8
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
44.8
43.2
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
6.6
0
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
6.6
13.3
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
50
9
9
0
9
0
0
0
0
0
9
9
0
% A
% Cys:
0
0
0
0
0
0
0
9
0
9
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
9
0
9
0
0
0
0
0
0
17
% D
% Glu:
9
0
0
0
0
0
9
0
0
0
9
0
0
0
0
% E
% Phe:
9
0
0
0
0
0
9
0
0
0
9
9
0
9
9
% F
% Gly:
9
0
9
0
0
0
0
0
0
0
0
0
9
0
0
% G
% His:
0
0
0
9
0
0
0
0
9
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
9
9
0
0
9
0
0
0
50
0
% I
% Lys:
0
59
17
59
9
17
0
0
17
0
17
0
0
0
0
% K
% Leu:
0
17
0
9
0
0
0
9
9
9
0
59
0
9
0
% L
% Met:
0
0
0
0
0
0
9
0
0
0
0
0
9
0
0
% M
% Asn:
0
9
0
0
0
0
0
0
50
0
0
0
0
0
9
% N
% Pro:
0
0
9
9
0
0
9
9
9
0
0
0
59
9
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
9
0
0
0
0
0
% Q
% Arg:
0
9
0
0
67
0
0
0
0
0
9
17
17
0
0
% R
% Ser:
9
0
9
0
0
59
0
0
0
0
59
9
0
0
9
% S
% Thr:
0
0
0
0
0
0
50
0
0
0
0
9
0
9
59
% T
% Val:
67
9
0
0
0
0
0
9
0
9
0
0
0
0
0
% V
% Trp:
0
0
0
9
9
9
0
0
9
0
0
0
0
0
0
% W
% Tyr:
0
0
9
0
9
0
0
59
0
59
0
0
0
9
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _