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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
GTF3C3
All Species:
26.67
Human Site:
Y246
Identified Species:
58.67
UniProt:
Q9Y5Q9
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9Y5Q9
NP_036218.1
886
101272
Y246
C
Y
T
K
A
L
K
Y
E
P
T
N
V
R
Y
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001087541
884
100933
Y244
C
Y
T
K
A
L
K
Y
E
P
T
N
V
R
Y
Dog
Lupus familis
XP_536013
883
100773
Y244
C
Y
T
K
A
L
K
Y
E
P
T
N
V
R
Y
Cat
Felis silvestris
Mouse
Mus musculus
NP_001028366
882
100602
Y242
C
Y
T
K
A
L
K
Y
E
P
T
N
V
R
Y
Rat
Rattus norvegicus
NP_001101709
883
100757
Y243
C
Y
T
K
A
L
K
Y
E
P
T
N
V
R
Y
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_001006515
910
103471
Y240
C
Y
A
K
A
L
K
Y
D
P
T
N
V
R
Y
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_700858
919
105160
Y267
C
Y
T
K
A
I
K
Y
D
S
S
N
V
Q
Y
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_611184
868
99608
M232
I
Y
T
K
A
I
K
M
L
P
K
V
Y
Q
L
Honey Bee
Apis mellifera
XP_001122295
804
92699
A227
C
Y
N
K
A
I
Q
A
N
P
K
D
I
N
L
Nematode Worm
Caenorhab. elegans
NP_505626
1037
118997
L350
C
Y
D
R
A
I
H
L
N
N
E
N
W
K
F
Sea Urchin
Strong. purpuratus
XP_001192537
809
92614
F220
C
Y
T
K
V
L
K
F
N
N
H
H
I
P
T
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
98.9
95.8
N.A.
93.4
93.4
N.A.
N.A.
86.6
N.A.
64.9
N.A.
29.6
31.3
25.4
37.3
Protein Similarity:
100
N.A.
99.4
98.1
N.A.
96.3
96.6
N.A.
N.A.
92.3
N.A.
79.8
N.A.
50.4
51
45.6
59.7
P-Site Identity:
100
N.A.
100
100
N.A.
100
100
N.A.
N.A.
86.6
N.A.
66.6
N.A.
40
33.3
26.6
40
P-Site Similarity:
100
N.A.
100
100
N.A.
100
100
N.A.
N.A.
93.3
N.A.
93.3
N.A.
53.3
60
53.3
60
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
10
0
91
0
0
10
0
0
0
0
0
0
0
% A
% Cys:
91
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
10
0
0
0
0
0
19
0
0
10
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
46
0
10
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
10
0
0
0
0
0
0
10
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
10
0
0
0
10
10
0
0
0
% H
% Ile:
10
0
0
0
0
37
0
0
0
0
0
0
19
0
0
% I
% Lys:
0
0
0
91
0
0
82
0
0
0
19
0
0
10
0
% K
% Leu:
0
0
0
0
0
64
0
10
10
0
0
0
0
0
19
% L
% Met:
0
0
0
0
0
0
0
10
0
0
0
0
0
0
0
% M
% Asn:
0
0
10
0
0
0
0
0
28
19
0
73
0
10
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
73
0
0
0
10
0
% P
% Gln:
0
0
0
0
0
0
10
0
0
0
0
0
0
19
0
% Q
% Arg:
0
0
0
10
0
0
0
0
0
0
0
0
0
55
0
% R
% Ser:
0
0
0
0
0
0
0
0
0
10
10
0
0
0
0
% S
% Thr:
0
0
73
0
0
0
0
0
0
0
55
0
0
0
10
% T
% Val:
0
0
0
0
10
0
0
0
0
0
0
10
64
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% W
% Tyr:
0
100
0
0
0
0
0
64
0
0
0
0
10
0
64
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _