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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
GTF3C3
All Species:
32.12
Human Site:
Y274
Identified Species:
70.67
UniProt:
Q9Y5Q9
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9Y5Q9
NP_036218.1
886
101272
Y274
H
K
M
A
M
D
G
Y
R
R
I
L
N
L
L
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001087541
884
100933
Y272
H
K
M
A
M
D
G
Y
R
R
I
L
N
L
L
Dog
Lupus familis
XP_536013
883
100773
Y272
H
K
M
A
M
D
G
Y
R
R
I
L
N
L
L
Cat
Felis silvestris
Mouse
Mus musculus
NP_001028366
882
100602
Y270
H
K
M
A
M
D
G
Y
R
R
I
L
N
L
L
Rat
Rattus norvegicus
NP_001101709
883
100757
Y271
H
K
M
A
M
D
G
Y
R
R
I
L
N
L
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_001006515
910
103471
Y268
H
K
L
A
M
D
G
Y
R
R
I
L
N
L
L
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_700858
919
105160
Y295
H
K
Q
A
M
D
G
Y
R
R
I
L
S
L
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_611184
868
99608
Y260
T
N
A
S
M
F
T
Y
L
K
M
L
P
L
M
Honey Bee
Apis mellifera
XP_001122295
804
92699
F255
K
R
A
Y
L
K
G
F
L
K
L
I
H
Q
L
Nematode Worm
Caenorhab. elegans
NP_505626
1037
118997
R378
R
P
L
A
M
R
T
R
L
Q
A
A
Q
L
I
Sea Urchin
Strong. purpuratus
XP_001192537
809
92614
Y248
N
K
K
A
M
E
S
Y
H
T
I
I
K
H
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
98.9
95.8
N.A.
93.4
93.4
N.A.
N.A.
86.6
N.A.
64.9
N.A.
29.6
31.3
25.4
37.3
Protein Similarity:
100
N.A.
99.4
98.1
N.A.
96.3
96.6
N.A.
N.A.
92.3
N.A.
79.8
N.A.
50.4
51
45.6
59.7
P-Site Identity:
100
N.A.
100
100
N.A.
100
100
N.A.
N.A.
93.3
N.A.
86.6
N.A.
26.6
13.3
20
40
P-Site Similarity:
100
N.A.
100
100
N.A.
100
100
N.A.
N.A.
100
N.A.
93.3
N.A.
53.3
60
40
60
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
19
82
0
0
0
0
0
0
10
10
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
64
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
10
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
10
0
10
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
73
0
0
0
0
0
0
0
0
% G
% His:
64
0
0
0
0
0
0
0
10
0
0
0
10
10
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
73
19
0
0
10
% I
% Lys:
10
73
10
0
0
10
0
0
0
19
0
0
10
0
0
% K
% Leu:
0
0
19
0
10
0
0
0
28
0
10
73
0
82
82
% L
% Met:
0
0
46
0
91
0
0
0
0
0
10
0
0
0
10
% M
% Asn:
10
10
0
0
0
0
0
0
0
0
0
0
55
0
0
% N
% Pro:
0
10
0
0
0
0
0
0
0
0
0
0
10
0
0
% P
% Gln:
0
0
10
0
0
0
0
0
0
10
0
0
10
10
0
% Q
% Arg:
10
10
0
0
0
10
0
10
64
64
0
0
0
0
0
% R
% Ser:
0
0
0
10
0
0
10
0
0
0
0
0
10
0
0
% S
% Thr:
10
0
0
0
0
0
19
0
0
10
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
10
0
0
0
82
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _