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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: GTF3C3 All Species: 26.97
Human Site: Y552 Identified Species: 59.33
UniProt: Q9Y5Q9 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9Y5Q9 NP_036218.1 886 101272 Y552 S Q G K M Y G Y V D T L L T M
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001087541 884 100933 Y550 S Q G K M Y G Y V D T L L T M
Dog Lupus familis XP_536013 883 100773 Y549 S Q G K M C G Y V D T L L T M
Cat Felis silvestris
Mouse Mus musculus NP_001028366 882 100602 Y548 S Q G K M Y G Y L D T L L T M
Rat Rattus norvegicus NP_001101709 883 100757 Y549 S Q G K M Y G Y L D T L L T M
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus NP_001006515 910 103471 Y576 S Q G K M Y G Y V D T L L T M
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_700858 919 105160 Y589 S Q G R M D D Y I D T V L T M
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_611184 868 99608 F527 Q I G R I E E F L D V G Y A L
Honey Bee Apis mellifera XP_001122295 804 92699 T515 V V R Q R L E T L Q L H R L S
Nematode Worm Caenorhab. elegans NP_505626 1037 118997 F675 E A G D S E Q F V R I T R M M
Sea Urchin Strong. purpuratus XP_001192537 809 92614 H516 T L M H T Q G H L Q E F V E K
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. 98.9 95.8 N.A. 93.4 93.4 N.A. N.A. 86.6 N.A. 64.9 N.A. 29.6 31.3 25.4 37.3
Protein Similarity: 100 N.A. 99.4 98.1 N.A. 96.3 96.6 N.A. N.A. 92.3 N.A. 79.8 N.A. 50.4 51 45.6 59.7
P-Site Identity: 100 N.A. 100 93.3 N.A. 93.3 93.3 N.A. N.A. 100 N.A. 66.6 N.A. 13.3 0 20 6.6
P-Site Similarity: 100 N.A. 100 93.3 N.A. 100 100 N.A. N.A. 100 N.A. 86.6 N.A. 46.6 13.3 26.6 33.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 10 0 0 0 0 0 0 0 0 0 0 0 10 0 % A
% Cys: 0 0 0 0 0 10 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 10 0 10 10 0 0 73 0 0 0 0 0 % D
% Glu: 10 0 0 0 0 19 19 0 0 0 10 0 0 10 0 % E
% Phe: 0 0 0 0 0 0 0 19 0 0 0 10 0 0 0 % F
% Gly: 0 0 82 0 0 0 64 0 0 0 0 10 0 0 0 % G
% His: 0 0 0 10 0 0 0 10 0 0 0 10 0 0 0 % H
% Ile: 0 10 0 0 10 0 0 0 10 0 10 0 0 0 0 % I
% Lys: 0 0 0 55 0 0 0 0 0 0 0 0 0 0 10 % K
% Leu: 0 10 0 0 0 10 0 0 46 0 10 55 64 10 10 % L
% Met: 0 0 10 0 64 0 0 0 0 0 0 0 0 10 73 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 10 64 0 10 0 10 10 0 0 19 0 0 0 0 0 % Q
% Arg: 0 0 10 19 10 0 0 0 0 10 0 0 19 0 0 % R
% Ser: 64 0 0 0 10 0 0 0 0 0 0 0 0 0 10 % S
% Thr: 10 0 0 0 10 0 0 10 0 0 64 10 0 64 0 % T
% Val: 10 10 0 0 0 0 0 0 46 0 10 10 10 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 46 0 64 0 0 0 0 10 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _