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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MMP24
All Species:
34.55
Human Site:
Y537
Identified Species:
84.44
UniProt:
Q9Y5R2
Number Species:
9
Phosphosite Substitution
Charge Score:
0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9Y5R2
NP_006681.1
645
73231
Y537
S
K
E
G
Y
Y
T
Y
F
Y
K
G
R
D
Y
Chimpanzee
Pan troglodytes
XP_001136415
624
71471
Y517
H
K
E
N
G
F
T
Y
F
Y
K
G
K
E
Y
Rhesus Macaque
Macaca mulatta
XP_001100890
574
66282
Y466
S
K
E
G
Y
Y
T
Y
F
Y
K
G
R
D
Y
Dog
Lupus familis
XP_542973
626
71946
Y518
S
K
E
G
Y
Y
T
Y
F
Y
K
G
R
D
Y
Cat
Felis silvestris
Mouse
Mus musculus
Q9R0S2
618
70472
Y510
S
K
E
G
Y
Y
T
Y
F
Y
K
G
R
D
Y
Rat
Rattus norvegicus
Q99PW6
618
70447
Y510
S
K
E
G
Y
Y
T
Y
F
Y
K
G
R
D
Y
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506645
616
70261
Y509
H
K
E
N
G
F
T
Y
F
Y
K
G
K
E
Y
Chicken
Gallus gallus
XP_417326
565
65155
Y457
S
K
E
G
F
Y
T
Y
F
Y
K
G
K
E
Y
Frog
Xenopus laevis
O13065
467
52794
D379
P
K
T
V
K
R
I
D
A
A
V
H
I
E
Q
Zebra Danio
Brachydanio rerio
XP_699803
608
69982
Y500
S
R
E
G
F
Y
T
Y
F
Y
K
G
K
D
Y
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
63.8
88
88.8
N.A.
92.7
93.1
N.A.
62.7
79
31.3
75.1
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
75.8
88.5
90.8
N.A.
93.8
94.2
N.A.
75.8
84
43.5
82.4
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
60
100
100
N.A.
100
100
N.A.
60
80
6.6
80
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
80
100
100
N.A.
100
100
N.A.
80
100
13.3
100
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
10
10
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
10
0
0
0
0
0
60
0
% D
% Glu:
0
0
90
0
0
0
0
0
0
0
0
0
0
40
0
% E
% Phe:
0
0
0
0
20
20
0
0
90
0
0
0
0
0
0
% F
% Gly:
0
0
0
70
20
0
0
0
0
0
0
90
0
0
0
% G
% His:
20
0
0
0
0
0
0
0
0
0
0
10
0
0
0
% H
% Ile:
0
0
0
0
0
0
10
0
0
0
0
0
10
0
0
% I
% Lys:
0
90
0
0
10
0
0
0
0
0
90
0
40
0
0
% K
% Leu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
20
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% Q
% Arg:
0
10
0
0
0
10
0
0
0
0
0
0
50
0
0
% R
% Ser:
70
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% S
% Thr:
0
0
10
0
0
0
90
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
10
0
0
0
0
0
0
10
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
50
70
0
90
0
90
0
0
0
0
90
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _