KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HEMK1
All Species:
17.27
Human Site:
S309
Identified Species:
42.22
UniProt:
Q9Y5R4
Number Species:
9
Phosphosite Substitution
Charge Score:
0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9Y5R4
NP_057257.1
338
38231
S309
L
V
S
S
W
L
Q
S
R
P
D
L
Y
L
N
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001097923
338
38085
S309
L
V
S
S
W
L
Q
S
R
P
E
L
Y
L
N
Dog
Lupus familis
XP_533816
358
39937
S310
L
V
G
N
W
L
Q
S
Q
P
D
L
S
L
D
Cat
Felis silvestris
Mouse
Mus musculus
Q921L7
340
38190
S311
L
V
S
S
W
L
Q
S
H
P
D
L
H
L
S
Rat
Rattus norvegicus
NP_001100323
340
38149
S311
L
V
S
S
W
L
Q
S
Q
P
D
L
H
L
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001516646
137
15225
W116
V
Q
Y
V
L
G
E
W
D
F
Q
D
L
T
L
Chicken
Gallus gallus
XP_414261
352
39553
A323
M
V
E
D
W
L
T
A
Q
P
D
L
F
L
T
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001107891
342
38728
E312
V
I
Q
Q
L
V
M
E
T
M
P
E
F
I
Y
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_393324
349
39667
K322
Y
I
Q
F
F
T
K
K
Y
P
I
L
K
L
Q
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001201549
390
44295
E349
M
I
Q
E
W
L
V
E
H
P
A
F
S
V
Q
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
95.2
80.4
N.A.
77.3
78.5
N.A.
23.3
55.9
N.A.
42.6
N.A.
N.A.
36.9
N.A.
33.8
Protein Similarity:
100
N.A.
97.9
84.6
N.A.
87.3
88.5
N.A.
29.2
70.4
N.A.
57.3
N.A.
N.A.
54.7
N.A.
47.9
P-Site Identity:
100
N.A.
93.3
66.6
N.A.
80
80
N.A.
0
46.6
N.A.
0
N.A.
N.A.
20
N.A.
20
P-Site Similarity:
100
N.A.
100
86.6
N.A.
93.3
100
N.A.
13.3
73.3
N.A.
33.3
N.A.
N.A.
40
N.A.
40
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
10
0
0
10
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
10
0
0
0
0
10
0
50
10
0
0
10
% D
% Glu:
0
0
10
10
0
0
10
20
0
0
10
10
0
0
0
% E
% Phe:
0
0
0
10
10
0
0
0
0
10
0
10
20
0
0
% F
% Gly:
0
0
10
0
0
10
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
20
0
0
0
20
0
0
% H
% Ile:
0
30
0
0
0
0
0
0
0
0
10
0
0
10
0
% I
% Lys:
0
0
0
0
0
0
10
10
0
0
0
0
10
0
0
% K
% Leu:
50
0
0
0
20
70
0
0
0
0
0
70
10
70
10
% L
% Met:
20
0
0
0
0
0
10
0
0
10
0
0
0
0
0
% M
% Asn:
0
0
0
10
0
0
0
0
0
0
0
0
0
0
20
% N
% Pro:
0
0
0
0
0
0
0
0
0
80
10
0
0
0
0
% P
% Gln:
0
10
30
10
0
0
50
0
30
0
10
0
0
0
20
% Q
% Arg:
0
0
0
0
0
0
0
0
20
0
0
0
0
0
0
% R
% Ser:
0
0
40
40
0
0
0
50
0
0
0
0
20
0
20
% S
% Thr:
0
0
0
0
0
10
10
0
10
0
0
0
0
10
10
% T
% Val:
20
60
0
10
0
10
10
0
0
0
0
0
0
10
0
% V
% Trp:
0
0
0
0
70
0
0
10
0
0
0
0
0
0
0
% W
% Tyr:
10
0
10
0
0
0
0
0
10
0
0
0
20
0
10
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _