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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HEMK1
All Species:
4.55
Human Site:
T226
Identified Species:
11.11
UniProt:
Q9Y5R4
Number Species:
9
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9Y5R4
NP_057257.1
338
38231
T226
M
T
S
E
R
S
W
T
H
L
P
W
G
P
M
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001097923
338
38085
T226
M
T
S
E
R
S
W
T
H
L
P
W
G
P
V
Dog
Lupus familis
XP_533816
358
39937
H227
T
L
E
G
S
W
A
H
L
L
P
W
G
P
V
Cat
Felis silvestris
Mouse
Mus musculus
Q921L7
340
38190
H228
T
S
E
G
C
C
T
H
L
L
P
W
S
P
L
Rat
Rattus norvegicus
NP_001100323
340
38149
H228
T
S
E
G
C
C
T
H
L
L
P
W
G
P
M
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001516646
137
15225
P35
N
H
S
S
Q
A
G
P
V
T
A
V
D
L
V
Chicken
Gallus gallus
XP_414261
352
39553
H240
V
S
Y
G
S
A
K
H
L
L
P
W
G
P
M
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001107891
342
38728
I229
V
V
K
D
A
D
V
I
L
S
K
C
N
P
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_393324
349
39667
L239
S
K
N
E
S
K
N
L
D
L
N
S
K
I
F
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001201549
390
44295
H266
D
E
S
P
L
R
I
H
S
K
Y
G
T
R
Y
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
95.2
80.4
N.A.
77.3
78.5
N.A.
23.3
55.9
N.A.
42.6
N.A.
N.A.
36.9
N.A.
33.8
Protein Similarity:
100
N.A.
97.9
84.6
N.A.
87.3
88.5
N.A.
29.2
70.4
N.A.
57.3
N.A.
N.A.
54.7
N.A.
47.9
P-Site Identity:
100
N.A.
93.3
33.3
N.A.
26.6
40
N.A.
6.6
40
N.A.
6.6
N.A.
N.A.
13.3
N.A.
6.6
P-Site Similarity:
100
N.A.
100
40
N.A.
40
46.6
N.A.
26.6
60
N.A.
26.6
N.A.
N.A.
20
N.A.
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
10
20
10
0
0
0
10
0
0
0
0
% A
% Cys:
0
0
0
0
20
20
0
0
0
0
0
10
0
0
0
% C
% Asp:
10
0
0
10
0
10
0
0
10
0
0
0
10
0
0
% D
% Glu:
0
10
30
30
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% F
% Gly:
0
0
0
40
0
0
10
0
0
0
0
10
50
0
0
% G
% His:
0
10
0
0
0
0
0
50
20
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
10
10
0
0
0
0
0
10
0
% I
% Lys:
0
10
10
0
0
10
10
0
0
10
10
0
10
0
0
% K
% Leu:
0
10
0
0
10
0
0
10
50
70
0
0
0
10
10
% L
% Met:
20
0
0
0
0
0
0
0
0
0
0
0
0
0
30
% M
% Asn:
10
0
10
0
0
0
10
0
0
0
10
0
10
0
0
% N
% Pro:
0
0
0
10
0
0
0
10
0
0
60
0
0
70
0
% P
% Gln:
0
0
0
0
10
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
20
10
0
0
0
0
0
0
0
10
0
% R
% Ser:
10
30
40
10
30
20
0
0
10
10
0
10
10
0
0
% S
% Thr:
30
20
0
0
0
0
20
20
0
10
0
0
10
0
0
% T
% Val:
20
10
0
0
0
0
10
0
10
0
0
10
0
0
40
% V
% Trp:
0
0
0
0
0
10
20
0
0
0
0
60
0
0
0
% W
% Tyr:
0
0
10
0
0
0
0
0
0
0
10
0
0
0
10
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _