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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CDC42BPB All Species: 22.73
Human Site: S475 Identified Species: 55.56
UniProt: Q9Y5S2 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0.11
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9Y5S2 NP_006026.3 1711 194315 S475 V Q S L H G S S R A L S N S N
Chimpanzee Pan troglodytes XP_510180 1757 198525 S521 V Q S L H G S S R A L S N S N
Rhesus Macaque Macaca mulatta XP_001088134 1781 202813 T476 V Q A L Q Y S T V D G P L T A
Dog Lupus familis XP_547990 1676 190919 T475 V Q S L H G S T R A L G S S A
Cat Felis silvestris
Mouse Mus musculus Q7TT50 1713 194762 T475 V Q S L H G S T R A L G N S N
Rat Rattus norvegicus Q7TT49 1713 194869 T475 V Q S L H G S T R A L G N S N
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001507902 1772 201257 T535 V Q S L H S S T R A A G N T N
Chicken Gallus gallus
Frog Xenopus laevis
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9W1B0 1637 186706 V502 L S K Q H N E V F E R L K T Q
Honey Bee Apis mellifera XP_395596 1741 197744 A522 A I K D K L D A Q E K L K L Q
Nematode Worm Caenorhab. elegans P92199 1173 135756 E81 I G R G A F G E V H L V R H T
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 94.9 59.9 89.9 N.A. 91.8 92 N.A. 83.4 N.A. N.A. N.A. N.A. 43 46.8 24.2 N.A.
Protein Similarity: 100 95.6 76.3 94 N.A. 96.5 96.4 N.A. 89.6 N.A. N.A. N.A. N.A. 62.7 65.1 43.3 N.A.
P-Site Identity: 100 100 26.6 73.3 N.A. 86.6 86.6 N.A. 66.6 N.A. N.A. N.A. N.A. 6.6 0 6.6 N.A.
P-Site Similarity: 100 100 46.6 86.6 N.A. 93.3 93.3 N.A. 80 N.A. N.A. N.A. N.A. 20 13.3 13.3 N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 10 0 10 0 10 0 0 10 0 60 10 0 0 0 20 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 10 0 0 10 0 0 10 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 10 10 0 20 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 10 0 0 10 0 0 0 0 0 0 % F
% Gly: 0 10 0 10 0 50 10 0 0 0 10 40 0 0 0 % G
% His: 0 0 0 0 70 0 0 0 0 10 0 0 0 10 0 % H
% Ile: 10 10 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 20 0 10 0 0 0 0 0 10 0 20 0 0 % K
% Leu: 10 0 0 70 0 10 0 0 0 0 60 20 10 10 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 10 0 0 0 0 0 0 50 0 50 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 10 0 0 0 % P
% Gln: 0 70 0 10 10 0 0 0 10 0 0 0 0 0 20 % Q
% Arg: 0 0 10 0 0 0 0 0 60 0 10 0 10 0 0 % R
% Ser: 0 10 60 0 0 10 70 20 0 0 0 20 10 50 0 % S
% Thr: 0 0 0 0 0 0 0 50 0 0 0 0 0 30 10 % T
% Val: 70 0 0 0 0 0 0 10 20 0 0 10 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 10 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _