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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
USP16
All Species:
22.73
Human Site:
T146
Identified Species:
45.45
UniProt:
Q9Y5T5
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9Y5T5
NP_001001992.1
823
93570
T146
R
K
Q
A
S
I
T
T
P
K
P
A
E
K
D
Chimpanzee
Pan troglodytes
XP_514854
826
93829
T146
R
K
Q
A
G
I
T
T
P
K
P
A
E
K
D
Rhesus Macaque
Macaca mulatta
XP_001102149
826
94000
T146
R
K
Q
A
G
I
T
T
P
K
P
A
E
K
D
Dog
Lupus familis
XP_848330
826
93971
T146
R
K
Q
A
G
I
T
T
P
K
S
A
A
K
D
Cat
Felis silvestris
Mouse
Mus musculus
Q99LG0
825
93388
T145
R
K
Q
A
G
V
R
T
S
K
P
A
E
K
N
Rat
Rattus norvegicus
Q2KJ09
826
93743
T145
R
K
Q
A
G
R
I
T
S
K
P
A
E
K
N
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506389
799
87920
V154
V
D
F
L
Q
K
H
V
S
K
T
E
A
S
S
Chicken
Gallus gallus
XP_416693
810
92233
S138
K
K
Q
V
C
V
N
S
S
H
L
E
K
Q
Q
Frog
Xenopus laevis
Q6PAW2
901
101274
N143
Q
R
K
A
K
A
K
N
K
N
S
N
S
V
V
Zebra Danio
Brachydanio rerio
A8HAL1
815
90431
P147
R
K
Q
V
L
T
A
P
D
K
R
N
A
S
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_001121285
844
94413
T156
K
K
S
T
T
S
I
T
S
S
Q
T
K
M
S
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_790411
1122
123641
K157
K
K
Q
A
F
Q
Q
K
P
A
E
K
S
A
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.7
98.1
92.1
N.A.
82.9
83.6
N.A.
39.2
63
51.9
48.5
N.A.
N.A.
29.8
N.A.
31.9
Protein Similarity:
100
99.3
99
96.4
N.A.
90.6
91.6
N.A.
56.7
77.2
66.6
65.1
N.A.
N.A.
45.6
N.A.
46.9
P-Site Identity:
100
93.3
93.3
80
N.A.
66.6
66.6
N.A.
6.6
13.3
6.6
26.6
N.A.
N.A.
13.3
N.A.
26.6
P-Site Similarity:
100
93.3
93.3
80
N.A.
80
73.3
N.A.
6.6
46.6
26.6
26.6
N.A.
N.A.
33.3
N.A.
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
67
0
9
9
0
0
9
0
50
25
9
0
% A
% Cys:
0
0
0
0
9
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
9
0
0
0
0
0
0
9
0
0
0
0
0
34
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
9
17
42
0
0
% E
% Phe:
0
0
9
0
9
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
42
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
9
0
0
9
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
34
17
0
0
0
0
0
0
0
0
% I
% Lys:
25
84
9
0
9
9
9
9
9
67
0
9
17
50
9
% K
% Leu:
0
0
0
9
9
0
0
0
0
0
9
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
9
0
% M
% Asn:
0
0
0
0
0
0
9
9
0
9
0
17
0
0
17
% N
% Pro:
0
0
0
0
0
0
0
9
42
0
42
0
0
0
0
% P
% Gln:
9
0
75
0
9
9
9
0
0
0
9
0
0
9
9
% Q
% Arg:
59
9
0
0
0
9
9
0
0
0
9
0
0
0
0
% R
% Ser:
0
0
9
0
9
9
0
9
42
9
17
0
17
17
25
% S
% Thr:
0
0
0
9
9
9
34
59
0
0
9
9
0
0
0
% T
% Val:
9
0
0
17
0
17
0
9
0
0
0
0
0
9
9
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _