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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
USP16
All Species:
26.36
Human Site:
Y345
Identified Species:
52.73
UniProt:
Q9Y5T5
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9Y5T5
NP_001001992.1
823
93570
Y345
L
K
N
K
V
K
D
Y
E
K
K
K
S
M
P
Chimpanzee
Pan troglodytes
XP_514854
826
93829
Y345
L
K
N
K
V
K
D
Y
E
K
K
K
S
I
P
Rhesus Macaque
Macaca mulatta
XP_001102149
826
94000
Y345
L
K
N
K
V
K
D
Y
E
K
K
K
S
I
P
Dog
Lupus familis
XP_848330
826
93971
Y344
L
K
N
K
V
K
D
Y
E
K
K
K
S
V
P
Cat
Felis silvestris
Mouse
Mus musculus
Q99LG0
825
93388
Y344
V
K
N
K
V
K
D
Y
E
K
K
K
A
I
P
Rat
Rattus norvegicus
Q2KJ09
826
93743
Y344
V
K
N
K
V
K
D
Y
E
K
K
K
A
I
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506389
799
87920
A342
E
T
R
K
K
V
K
A
Y
G
R
E
G
V
K
Chicken
Gallus gallus
XP_416693
810
92233
Y332
L
R
K
K
I
K
E
Y
E
K
K
K
G
I
K
Frog
Xenopus laevis
Q6PAW2
901
101274
K347
K
I
V
K
D
Y
E
K
R
R
T
I
P
N
F
Zebra Danio
Brachydanio rerio
A8HAL1
815
90431
E357
Q
T
K
K
I
V
K
E
Y
E
K
D
G
A
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_001121285
844
94413
G354
K
S
R
V
K
F
Y
G
N
Q
A
N
S
R
L
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_790411
1122
123641
I366
D
E
A
T
K
K
K
I
K
E
Y
G
S
H
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.7
98.1
92.1
N.A.
82.9
83.6
N.A.
39.2
63
51.9
48.5
N.A.
N.A.
29.8
N.A.
31.9
Protein Similarity:
100
99.3
99
96.4
N.A.
90.6
91.6
N.A.
56.7
77.2
66.6
65.1
N.A.
N.A.
45.6
N.A.
46.9
P-Site Identity:
100
93.3
93.3
93.3
N.A.
80
80
N.A.
6.6
53.3
6.6
20
N.A.
N.A.
6.6
N.A.
13.3
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
26.6
80
20
33.3
N.A.
N.A.
13.3
N.A.
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
9
0
0
0
0
9
0
0
9
0
17
9
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
9
0
0
0
9
0
50
0
0
0
0
9
0
0
0
% D
% Glu:
9
9
0
0
0
0
17
9
59
17
0
9
0
0
0
% E
% Phe:
0
0
0
0
0
9
0
0
0
0
0
0
0
0
9
% F
% Gly:
0
0
0
0
0
0
0
9
0
9
0
9
25
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
9
0
% H
% Ile:
0
9
0
0
17
0
0
9
0
0
0
9
0
42
0
% I
% Lys:
17
50
17
84
25
67
25
9
9
59
67
59
0
0
17
% K
% Leu:
42
0
0
0
0
0
0
0
0
0
0
0
0
0
9
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
9
0
% M
% Asn:
0
0
50
0
0
0
0
0
9
0
0
9
0
9
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
9
0
59
% P
% Gln:
9
0
0
0
0
0
0
0
0
9
0
0
0
0
0
% Q
% Arg:
0
9
17
0
0
0
0
0
9
9
9
0
0
9
0
% R
% Ser:
0
9
0
0
0
0
0
0
0
0
0
0
50
0
9
% S
% Thr:
0
17
0
9
0
0
0
0
0
0
9
0
0
0
0
% T
% Val:
17
0
9
9
50
17
0
0
0
0
0
0
0
17
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
9
9
59
17
0
9
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _