KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
USP16
All Species:
14.24
Human Site:
Y424
Identified Species:
28.48
UniProt:
Q9Y5T5
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9Y5T5
NP_001001992.1
823
93570
Y424
E
E
K
D
N
D
S
Y
I
K
E
R
S
D
I
Chimpanzee
Pan troglodytes
XP_514854
826
93829
Y424
E
E
K
D
N
D
S
Y
I
K
E
R
S
D
I
Rhesus Macaque
Macaca mulatta
XP_001102149
826
94000
Y424
E
E
K
D
N
D
S
Y
I
K
E
R
S
D
I
Dog
Lupus familis
XP_848330
826
93971
Y423
E
E
K
D
N
D
S
Y
M
K
E
R
S
D
I
Cat
Felis silvestris
Mouse
Mus musculus
Q99LG0
825
93388
M423
E
E
K
D
D
S
Y
M
K
S
R
S
D
L
P
Rat
Rattus norvegicus
Q2KJ09
826
93743
M423
E
E
K
D
D
S
Y
M
K
T
R
S
D
V
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506389
799
87920
T421
Q
Y
S
C
S
A
V
T
A
V
N
H
Q
Q
P
Chicken
Gallus gallus
XP_416693
810
92233
I411
D
K
N
N
D
Y
Y
I
K
Q
R
D
E
P
P
Frog
Xenopus laevis
Q6PAW2
901
101274
R426
D
D
R
Y
V
K
E
R
D
E
V
S
P
G
A
Zebra Danio
Brachydanio rerio
A8HAL1
815
90431
G436
D
T
S
S
L
A
N
G
N
E
D
M
P
T
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_001121285
844
94413
Q433
S
H
V
P
S
K
H
Q
L
K
K
E
K
K
A
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_790411
1122
123641
Q445
S
S
N
D
G
D
K
Q
T
L
A
A
T
A
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.7
98.1
92.1
N.A.
82.9
83.6
N.A.
39.2
63
51.9
48.5
N.A.
N.A.
29.8
N.A.
31.9
Protein Similarity:
100
99.3
99
96.4
N.A.
90.6
91.6
N.A.
56.7
77.2
66.6
65.1
N.A.
N.A.
45.6
N.A.
46.9
P-Site Identity:
100
100
100
93.3
N.A.
26.6
26.6
N.A.
0
0
0
0
N.A.
N.A.
6.6
N.A.
13.3
P-Site Similarity:
100
100
100
100
N.A.
33.3
33.3
N.A.
13.3
33.3
26.6
26.6
N.A.
N.A.
26.6
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
17
0
0
9
0
9
9
0
9
25
% A
% Cys:
0
0
0
9
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
25
9
0
59
25
42
0
0
9
0
9
9
17
34
0
% D
% Glu:
50
50
0
0
0
0
9
0
0
17
34
9
9
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
9
0
0
9
0
0
0
0
0
9
9
% G
% His:
0
9
0
0
0
0
9
0
0
0
0
9
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
9
25
0
0
0
0
0
34
% I
% Lys:
0
9
50
0
0
17
9
0
25
42
9
0
9
9
0
% K
% Leu:
0
0
0
0
9
0
0
0
9
9
0
0
0
9
0
% L
% Met:
0
0
0
0
0
0
0
17
9
0
0
9
0
0
0
% M
% Asn:
0
0
17
9
34
0
9
0
9
0
9
0
0
0
0
% N
% Pro:
0
0
0
9
0
0
0
0
0
0
0
0
17
9
34
% P
% Gln:
9
0
0
0
0
0
0
17
0
9
0
0
9
9
0
% Q
% Arg:
0
0
9
0
0
0
0
9
0
0
25
34
0
0
0
% R
% Ser:
17
9
17
9
17
17
34
0
0
9
0
25
34
0
0
% S
% Thr:
0
9
0
0
0
0
0
9
9
9
0
0
9
9
0
% T
% Val:
0
0
9
0
9
0
9
0
0
9
9
0
0
9
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
9
0
9
0
9
25
34
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _