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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
USP16
All Species:
15.45
Human Site:
Y508
Identified Species:
30.91
UniProt:
Q9Y5T5
Number Species:
11
Phosphosite Substitution
Charge Score:
0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9Y5T5
NP_001001992.1
823
93570
Y508
E
G
V
M
H
K
E
Y
C
V
N
Q
K
D
L
Chimpanzee
Pan troglodytes
XP_514854
826
93829
Y508
E
G
V
M
H
K
E
Y
C
V
N
Q
K
D
L
Rhesus Macaque
Macaca mulatta
XP_001102149
826
94000
Y508
E
G
V
M
H
K
E
Y
C
V
N
Q
K
D
L
Dog
Lupus familis
XP_848330
826
93971
Y507
E
E
I
T
H
K
E
Y
C
V
N
Q
K
D
L
Cat
Felis silvestris
Mouse
Mus musculus
Q99LG0
825
93388
I506
S
Q
E
E
A
T
Q
I
E
L
S
V
N
Q
K
Rat
Rattus norvegicus
Q2KJ09
826
93743
T506
S
Q
E
E
L
T
Q
T
E
L
C
A
N
Q
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506389
799
87920
D487
P
S
I
L
T
P
Q
D
V
H
R
A
E
A
A
Chicken
Gallus gallus
XP_416693
810
92233
S488
D
V
K
Q
E
E
E
S
S
N
D
C
K
D
D
Frog
Xenopus laevis
Q6PAW2
901
101274
M544
M
A
G
G
F
K
T
M
E
M
D
L
S
T
L
Zebra Danio
Brachydanio rerio
A8HAL1
815
90431
H520
E
D
L
S
L
E
K
H
N
E
D
Q
D
D
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_001121285
844
94413
Q503
S
G
Y
S
S
E
K
Q
S
T
L
A
S
P
A
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_790411
1122
123641
G519
E
R
R
E
E
G
V
G
Y
R
D
P
N
D
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.7
98.1
92.1
N.A.
82.9
83.6
N.A.
39.2
63
51.9
48.5
N.A.
N.A.
29.8
N.A.
31.9
Protein Similarity:
100
99.3
99
96.4
N.A.
90.6
91.6
N.A.
56.7
77.2
66.6
65.1
N.A.
N.A.
45.6
N.A.
46.9
P-Site Identity:
100
100
100
80
N.A.
0
0
N.A.
0
20
13.3
20
N.A.
N.A.
6.6
N.A.
13.3
P-Site Similarity:
100
100
100
86.6
N.A.
20
13.3
N.A.
26.6
40
26.6
53.3
N.A.
N.A.
20
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
9
0
0
9
0
0
0
0
0
0
25
0
9
25
% A
% Cys:
0
0
0
0
0
0
0
0
34
0
9
9
0
0
0
% C
% Asp:
9
9
0
0
0
0
0
9
0
0
34
0
9
59
9
% D
% Glu:
50
9
17
25
17
25
42
0
25
9
0
0
9
0
9
% E
% Phe:
0
0
0
0
9
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
34
9
9
0
9
0
9
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
34
0
0
9
0
9
0
0
0
0
0
% H
% Ile:
0
0
17
0
0
0
0
9
0
0
0
0
0
0
0
% I
% Lys:
0
0
9
0
0
42
17
0
0
0
0
0
42
0
17
% K
% Leu:
0
0
9
9
17
0
0
0
0
17
9
9
0
0
42
% L
% Met:
9
0
0
25
0
0
0
9
0
9
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
9
9
34
0
25
0
0
% N
% Pro:
9
0
0
0
0
9
0
0
0
0
0
9
0
9
0
% P
% Gln:
0
17
0
9
0
0
25
9
0
0
0
42
0
17
0
% Q
% Arg:
0
9
9
0
0
0
0
0
0
9
9
0
0
0
0
% R
% Ser:
25
9
0
17
9
0
0
9
17
0
9
0
17
0
0
% S
% Thr:
0
0
0
9
9
17
9
9
0
9
0
0
0
9
0
% T
% Val:
0
9
25
0
0
0
9
0
9
34
0
9
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
9
0
0
0
0
34
9
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _