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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TSSC4
All Species:
6.36
Human Site:
T248
Identified Species:
15.56
UniProt:
Q9Y5U2
Number Species:
9
Phosphosite Substitution
Charge Score:
0.22
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9Y5U2
NP_005697.2
329
34285
T248
G
G
L
G
N
P
A
T
D
R
G
E
G
P
V
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001093561
329
34005
T248
G
G
L
G
N
P
A
T
D
R
G
E
G
P
V
Dog
Lupus familis
XP_854387
320
33585
A239
G
A
P
G
D
L
G
A
A
G
G
E
G
P
V
Cat
Felis silvestris
Mouse
Mus musculus
Q9JHE7
317
33551
V233
K
R
V
L
K
K
G
V
G
S
G
A
G
G
E
Rat
Rattus norvegicus
Q5XIB1
317
33920
V233
K
R
V
L
K
K
G
V
V
S
G
A
G
G
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_001006470
340
36852
T255
G
D
K
K
H
I
K
T
D
L
K
G
K
S
V
Frog
Xenopus laevis
NP_001088577
288
31802
E210
Q
D
S
S
S
P
G
E
S
K
I
L
F
T
R
Zebra Danio
Brachydanio rerio
Q0P4A6
306
34121
D228
D
Q
S
G
S
R
A
D
H
A
K
K
E
E
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_648377
233
26232
I155
S
P
P
T
D
G
K
I
E
F
K
R
T
S
K
Honey Bee
Apis mellifera
XP_001122509
249
28931
S171
K
S
K
K
K
K
I
S
T
E
I
G
F
K
K
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
96.6
68
N.A.
62.6
63.2
N.A.
N.A.
45.8
28.5
28.8
N.A.
22.7
20.3
N.A.
N.A.
Protein Similarity:
100
N.A.
97.8
75.6
N.A.
71.1
71.1
N.A.
N.A.
58.5
41.9
42.2
N.A.
35.8
37.9
N.A.
N.A.
P-Site Identity:
100
N.A.
100
46.6
N.A.
13.3
13.3
N.A.
N.A.
26.6
6.6
20
N.A.
0
0
N.A.
N.A.
P-Site Similarity:
100
N.A.
100
53.3
N.A.
20
20
N.A.
N.A.
33.3
20
33.3
N.A.
13.3
6.6
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
10
0
0
0
0
30
10
10
10
0
20
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
10
20
0
0
20
0
0
10
30
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
10
10
10
0
30
10
10
20
% E
% Phe:
0
0
0
0
0
0
0
0
0
10
0
0
20
0
0
% F
% Gly:
40
20
0
40
0
10
40
0
10
10
50
20
50
20
0
% G
% His:
0
0
0
0
10
0
0
0
10
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
10
10
10
0
0
20
0
0
0
0
% I
% Lys:
30
0
20
20
30
30
20
0
0
10
30
10
10
10
20
% K
% Leu:
0
0
20
20
0
10
0
0
0
10
0
10
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
20
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
10
20
0
0
30
0
0
0
0
0
0
0
30
0
% P
% Gln:
10
10
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
20
0
0
0
10
0
0
0
20
0
10
0
0
10
% R
% Ser:
10
10
20
10
20
0
0
10
10
20
0
0
0
20
0
% S
% Thr:
0
0
0
10
0
0
0
30
10
0
0
0
10
10
0
% T
% Val:
0
0
20
0
0
0
0
20
10
0
0
0
0
0
50
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _