KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
INSIG2
All Species:
10.3
Human Site:
S20
Identified Species:
45.33
UniProt:
Q9Y5U4
Number Species:
5
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9Y5U4
NP_057217.2
225
24778
S20
K
C
G
P
Y
I
S
S
V
T
S
Q
S
V
N
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
Q91WG1
225
24897
S20
K
C
G
P
Y
I
S
S
V
T
S
Q
S
V
N
Rat
Rattus norvegicus
Q80UA9
225
24950
S20
K
R
G
P
Y
I
S
S
V
T
S
Q
S
V
N
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q5ZMT9
252
27336
S51
E
R
E
A
S
G
G
S
A
T
T
W
R
Q
H
Frog
Xenopus laevis
Q66J27
218
24340
N20
P
I
L
A
Q
K
M
N
L
L
L
R
G
F
L
Zebra Danio
Brachydanio rerio
Q8AV61
251
27578
C30
S
S
A
G
W
I
V
C
K
T
G
E
M
M
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
N.A.
N.A.
N.A.
96.8
96.4
N.A.
N.A.
66.2
78.6
66.1
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
N.A.
N.A.
N.A.
N.A.
98.2
97.7
N.A.
N.A.
77.3
88.8
77.2
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
N.A.
N.A.
N.A.
N.A.
100
93.3
N.A.
N.A.
13.3
0
13.3
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
N.A.
N.A.
N.A.
N.A.
100
93.3
N.A.
N.A.
33.3
20
40
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
17
34
0
0
0
0
17
0
0
0
0
0
0
% A
% Cys:
0
34
0
0
0
0
0
17
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
17
0
17
0
0
0
0
0
0
0
0
17
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
17
0
% F
% Gly:
0
0
50
17
0
17
17
0
0
0
17
0
17
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
17
% H
% Ile:
0
17
0
0
0
67
0
0
0
0
0
0
0
0
0
% I
% Lys:
50
0
0
0
0
17
0
0
17
0
0
0
0
0
0
% K
% Leu:
0
0
17
0
0
0
0
0
17
17
17
0
0
0
17
% L
% Met:
0
0
0
0
0
0
17
0
0
0
0
0
17
17
0
% M
% Asn:
0
0
0
0
0
0
0
17
0
0
0
0
0
0
50
% N
% Pro:
17
0
0
50
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
17
0
0
0
0
0
0
50
0
17
0
% Q
% Arg:
0
34
0
0
0
0
0
0
0
0
0
17
17
0
0
% R
% Ser:
17
17
0
0
17
0
50
67
0
0
50
0
50
0
17
% S
% Thr:
0
0
0
0
0
0
0
0
0
84
17
0
0
0
0
% T
% Val:
0
0
0
0
0
0
17
0
50
0
0
0
0
50
0
% V
% Trp:
0
0
0
0
17
0
0
0
0
0
0
17
0
0
0
% W
% Tyr:
0
0
0
0
50
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _