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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
INSIG2
All Species:
13.64
Human Site:
Y187
Identified Species:
60
UniProt:
Q9Y5U4
Number Species:
5
Phosphosite Substitution
Charge Score:
0.4
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9Y5U4
NP_057217.2
225
24778
Y187
Y
T
S
P
D
F
L
Y
V
R
S
W
L
P
C
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
Q91WG1
225
24897
Y187
Y
T
S
P
D
F
L
Y
V
R
S
W
L
P
C
Rat
Rattus norvegicus
Q80UA9
225
24950
Y187
Y
T
S
P
D
F
L
Y
V
R
S
W
L
P
C
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q5ZMT9
252
27336
D215
V
Y
Q
Y
T
S
P
D
F
L
Y
I
R
S
W
Frog
Xenopus laevis
Q66J27
218
24340
Y180
Y
T
A
P
D
F
L
Y
V
R
S
W
L
P
C
Zebra Danio
Brachydanio rerio
Q8AV61
251
27578
D214
I
Y
Q
Y
T
S
P
D
F
L
Y
V
R
S
W
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
N.A.
N.A.
N.A.
96.8
96.4
N.A.
N.A.
66.2
78.6
66.1
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
N.A.
N.A.
N.A.
N.A.
98.2
97.7
N.A.
N.A.
77.3
88.8
77.2
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
N.A.
N.A.
N.A.
N.A.
100
100
N.A.
N.A.
0
93.3
0
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
N.A.
N.A.
N.A.
N.A.
100
100
N.A.
N.A.
0
100
0
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
17
0
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
67
% C
% Asp:
0
0
0
0
67
0
0
34
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
67
0
0
34
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
17
0
0
0
0
0
0
0
0
0
0
17
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
0
0
67
0
0
34
0
0
67
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
67
0
0
34
0
0
0
0
0
0
67
0
% P
% Gln:
0
0
34
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
67
0
0
34
0
0
% R
% Ser:
0
0
50
0
0
34
0
0
0
0
67
0
0
34
0
% S
% Thr:
0
67
0
0
34
0
0
0
0
0
0
0
0
0
0
% T
% Val:
17
0
0
0
0
0
0
0
67
0
0
17
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
67
0
0
34
% W
% Tyr:
67
34
0
34
0
0
0
67
0
0
34
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _