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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TNFRSF18
All Species:
5.15
Human Site:
S229
Identified Species:
18.89
UniProt:
Q9Y5U5
Number Species:
6
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9Y5U5
NP_004186.1
241
26000
S229
E
E
E
R
G
E
R
S
A
E
E
K
G
R
L
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_848560
227
24488
L215
E
E
E
R
G
E
Q
L
S
P
D
K
G
Q
L
Cat
Felis silvestris
Mouse
Mus musculus
O35714
228
25316
T217
E
E
E
R
G
E
Q
T
E
E
K
C
H
L
G
Rat
Rattus norvegicus
P15725
271
29877
W239
L
Y
L
L
R
K
A
W
R
S
P
N
T
P
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505421
270
29660
S251
E
E
E
E
G
E
C
S
D
C
C
E
S
L
R
Chicken
Gallus gallus
NP_001026045
258
29146
E228
P
Q
P
S
H
H
R
E
E
T
Y
S
C
Q
F
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001106996
259
29352
K235
S
E
S
C
K
L
S
K
E
E
R
G
E
S
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
N.A.
65.1
N.A.
55.1
22.8
N.A.
24.8
32.1
N.A.
25.8
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
N.A.
N.A.
73
N.A.
66.8
31.3
N.A.
42.5
45.7
N.A.
37
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
N.A.
N.A.
60
N.A.
46.6
0
N.A.
40
6.6
N.A.
13.3
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
N.A.
N.A.
86.6
N.A.
66.6
6.6
N.A.
46.6
20
N.A.
13.3
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
15
0
15
0
0
0
0
0
0
% A
% Cys:
0
0
0
15
0
0
15
0
0
15
15
15
15
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
15
0
15
0
0
0
15
% D
% Glu:
58
72
58
15
0
58
0
15
43
43
15
15
15
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
15
% F
% Gly:
0
0
0
0
58
0
0
0
0
0
0
15
29
0
15
% G
% His:
0
0
0
0
15
15
0
0
0
0
0
0
15
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
15
15
0
15
0
0
15
29
0
0
15
% K
% Leu:
15
0
15
15
0
15
0
15
0
0
0
0
0
29
29
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
15
0
0
0
% N
% Pro:
15
0
15
0
0
0
0
0
0
15
15
0
0
15
0
% P
% Gln:
0
15
0
0
0
0
29
0
0
0
0
0
0
29
0
% Q
% Arg:
0
0
0
43
15
0
29
0
15
0
15
0
0
15
15
% R
% Ser:
15
0
15
15
0
0
15
29
15
15
0
15
15
15
0
% S
% Thr:
0
0
0
0
0
0
0
15
0
15
0
0
15
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
15
0
0
0
0
0
0
0
% W
% Tyr:
0
15
0
0
0
0
0
0
0
0
15
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _