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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SNX8
All Species:
30.3
Human Site:
S421
Identified Species:
60.61
UniProt:
Q9Y5X2
Number Species:
11
Phosphosite Substitution
Charge Score:
0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9Y5X2
NP_037453.1
465
52569
S421
I
L
R
A
F
V
N
S
Q
I
Q
G
H
K
E
Chimpanzee
Pan troglodytes
XP_001136580
465
52480
S421
I
L
R
A
F
V
N
S
Q
I
Q
G
H
K
E
Rhesus Macaque
Macaca mulatta
XP_001086393
465
52528
S421
I
L
R
A
F
V
N
S
Q
I
Q
G
H
K
E
Dog
Lupus familis
XP_536895
463
52455
S420
I
L
G
A
F
V
N
S
Q
I
Q
G
H
K
E
Cat
Felis silvestris
Mouse
Mus musculus
Q8CFD4
459
52040
S415
I
L
G
A
F
V
N
S
Q
I
Q
G
H
K
E
Rat
Rattus norvegicus
NP_001099382
463
52639
S419
I
L
G
A
F
V
N
S
Q
I
Q
G
H
K
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513587
432
49865
S388
I
L
G
A
F
V
N
S
Q
I
Q
G
H
K
E
Chicken
Gallus gallus
XP_414774
412
47202
S368
I
L
G
A
F
V
N
S
Q
I
Q
G
H
K
E
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q566W7
430
49451
N385
D
W
D
R
W
Q
N
N
K
R
Q
D
F
R
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_396294
516
58366
M459
F
S
L
H
C
L
H
M
E
T
Q
L
V
H
A
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_781083
388
44160
G346
L
C
E
R
H
E
K
G
V
L
R
D
H
Q
N
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P40959
511
59638
E462
L
I
R
Q
C
I
L
E
E
F
T
I
F
Q
E
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.3
98
84.7
N.A.
88.3
87.9
N.A.
83.2
78
N.A.
22.1
N.A.
N.A.
37.5
N.A.
38.2
Protein Similarity:
100
99.7
98.4
90.7
N.A.
93.3
93.1
N.A.
87.3
83.2
N.A.
41
N.A.
N.A.
58.7
N.A.
54.4
P-Site Identity:
100
100
100
93.3
N.A.
93.3
93.3
N.A.
93.3
93.3
N.A.
13.3
N.A.
N.A.
6.6
N.A.
6.6
P-Site Similarity:
100
100
100
93.3
N.A.
93.3
93.3
N.A.
93.3
93.3
N.A.
46.6
N.A.
N.A.
26.6
N.A.
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
21.7
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
40.9
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
46.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
67
0
0
0
0
0
0
0
0
0
0
9
% A
% Cys:
0
9
0
0
17
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
9
0
9
0
0
0
0
0
0
0
0
17
0
0
0
% D
% Glu:
0
0
9
0
0
9
0
9
17
0
0
0
0
0
75
% E
% Phe:
9
0
0
0
67
0
0
0
0
9
0
0
17
0
0
% F
% Gly:
0
0
42
0
0
0
0
9
0
0
0
67
0
0
0
% G
% His:
0
0
0
9
9
0
9
0
0
0
0
0
75
9
0
% H
% Ile:
67
9
0
0
0
9
0
0
0
67
0
9
0
0
0
% I
% Lys:
0
0
0
0
0
0
9
0
9
0
0
0
0
67
0
% K
% Leu:
17
67
9
0
0
9
9
0
0
9
0
9
0
0
0
% L
% Met:
0
0
0
0
0
0
0
9
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
75
9
0
0
0
0
0
0
9
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
9
0
9
0
0
67
0
84
0
0
17
9
% Q
% Arg:
0
0
34
17
0
0
0
0
0
9
9
0
0
9
0
% R
% Ser:
0
9
0
0
0
0
0
67
0
0
0
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
9
9
0
0
0
0
% T
% Val:
0
0
0
0
0
67
0
0
9
0
0
0
9
0
0
% V
% Trp:
0
9
0
0
9
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _