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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SNX8 All Species: 23.64
Human Site: S456 Identified Species: 47.27
UniProt: Q9Y5X2 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9Y5X2 NP_037453.1 465 52569 S456 S T L T P P C S P P E D G L C
Chimpanzee Pan troglodytes XP_001136580 465 52480 S456 S T L T P P C S P P E D G L C
Rhesus Macaque Macaca mulatta XP_001086393 465 52528 S456 S A L T P P C S P P E D G L C
Dog Lupus familis XP_536895 463 52455 S455 S S L T L P R S P Q D G V S P
Cat Felis silvestris
Mouse Mus musculus Q8CFD4 459 52040 S450 S V L T P P R S P Q E D G V C
Rat Rattus norvegicus NP_001099382 463 52639 S454 S V L T P P R S P Q E D G M C
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001513587 432 49865 S423 N M P T P P R S P Q E D N L F
Chicken Gallus gallus XP_414774 412 47202 S403 N M P T P P L S P P D G N F F
Frog Xenopus laevis
Zebra Danio Brachydanio rerio Q566W7 430 49451 Q420 E S L I P L L Q D K Q D A K G
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_396294 516 58366 K494 S E L A E V W K L I E P T I M
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_781083 388 44160 Q381 E Y V N E V E Q L E S R I I E
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P40959 511 59638 E497 G L K L N E W E K L V T S I M
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.3 98 84.7 N.A. 88.3 87.9 N.A. 83.2 78 N.A. 22.1 N.A. N.A. 37.5 N.A. 38.2
Protein Similarity: 100 99.7 98.4 90.7 N.A. 93.3 93.1 N.A. 87.3 83.2 N.A. 41 N.A. N.A. 58.7 N.A. 54.4
P-Site Identity: 100 100 93.3 40 N.A. 73.3 73.3 N.A. 53.3 40 N.A. 20 N.A. N.A. 20 N.A. 0
P-Site Similarity: 100 100 93.3 53.3 N.A. 80 80 N.A. 60 53.3 N.A. 33.3 N.A. N.A. 26.6 N.A. 13.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. 21.7 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 40.9 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 0 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 6.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 9 0 9 0 0 0 0 0 0 0 0 9 0 0 % A
% Cys: 0 0 0 0 0 0 25 0 0 0 0 0 0 0 42 % C
% Asp: 0 0 0 0 0 0 0 0 9 0 17 59 0 0 0 % D
% Glu: 17 9 0 0 17 9 9 9 0 9 59 0 0 0 9 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 9 17 % F
% Gly: 9 0 0 0 0 0 0 0 0 0 0 17 42 0 9 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 9 0 0 0 0 0 9 0 0 9 25 0 % I
% Lys: 0 0 9 0 0 0 0 9 9 9 0 0 0 9 0 % K
% Leu: 0 9 67 9 9 9 17 0 17 9 0 0 0 34 0 % L
% Met: 0 17 0 0 0 0 0 0 0 0 0 0 0 9 17 % M
% Asn: 17 0 0 9 9 0 0 0 0 0 0 0 17 0 0 % N
% Pro: 0 0 17 0 67 67 0 0 67 34 0 9 0 0 9 % P
% Gln: 0 0 0 0 0 0 0 17 0 34 9 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 34 0 0 0 0 9 0 0 0 % R
% Ser: 59 17 0 0 0 0 0 67 0 0 9 0 9 9 0 % S
% Thr: 0 17 0 67 0 0 0 0 0 0 0 9 9 0 0 % T
% Val: 0 17 9 0 0 17 0 0 0 0 9 0 9 9 0 % V
% Trp: 0 0 0 0 0 0 17 0 0 0 0 0 0 0 0 % W
% Tyr: 0 9 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _