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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SNX8 All Species: 8.18
Human Site: S52 Identified Species: 16.36
UniProt: Q9Y5X2 Number Species: 11
    Phosphosite Substitution
    Charge Score: -0.18
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9Y5X2 NP_037453.1 465 52569 S52 V Q Q V P A P S R M Q M P Q G
Chimpanzee Pan troglodytes XP_001136580 465 52480 S52 V Q Q A P A P S R M Q M P Q G
Rhesus Macaque Macaca mulatta XP_001086393 465 52528 S52 V Q Q A A A P S R M Q M P Q G
Dog Lupus familis XP_536895 463 52455 N51 E R R D P Y P N R M Q M P Q G
Cat Felis silvestris
Mouse Mus musculus Q8CFD4 459 52040 G47 E W R A L D P G R M Q M P Q G
Rat Rattus norvegicus NP_001099382 463 52639 R47 E W R N L D P R R M Q M P Q G
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001513587 432 49865 K41 T L Q E L L A K D T I Q V E L
Chicken Gallus gallus XP_414774 412 47202 E41 G L F L K H V E Y E V S S K R
Frog Xenopus laevis
Zebra Danio Brachydanio rerio Q566W7 430 49451 N50 E K D L S L P N G T P V D T S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_396294 516 58366 A112 L S E V T L L A Q R L H K G S
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_781083 388 44160 K36 Q G K Q P N V K L L E N Y T G
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P40959 511 59638 Q104 D K N D A R D Q N I E E S E A
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.3 98 84.7 N.A. 88.3 87.9 N.A. 83.2 78 N.A. 22.1 N.A. N.A. 37.5 N.A. 38.2
Protein Similarity: 100 99.7 98.4 90.7 N.A. 93.3 93.1 N.A. 87.3 83.2 N.A. 41 N.A. N.A. 58.7 N.A. 54.4
P-Site Identity: 100 93.3 86.6 60 N.A. 53.3 53.3 N.A. 6.6 0 N.A. 6.6 N.A. N.A. 6.6 N.A. 13.3
P-Site Similarity: 100 93.3 86.6 80 N.A. 60 60 N.A. 13.3 13.3 N.A. 33.3 N.A. N.A. 33.3 N.A. 33.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. 21.7 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 40.9 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 0 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 26.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 25 17 25 9 9 0 0 0 0 0 0 9 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 9 0 9 17 0 17 9 0 9 0 0 0 9 0 0 % D
% Glu: 34 0 9 9 0 0 0 9 0 9 17 9 0 17 0 % E
% Phe: 0 0 9 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 9 9 0 0 0 0 0 9 9 0 0 0 0 9 59 % G
% His: 0 0 0 0 0 9 0 0 0 0 0 9 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 9 9 0 0 0 0 % I
% Lys: 0 17 9 0 9 0 0 17 0 0 0 0 9 9 0 % K
% Leu: 9 17 0 17 25 25 9 0 9 9 9 0 0 0 9 % L
% Met: 0 0 0 0 0 0 0 0 0 50 0 50 0 0 0 % M
% Asn: 0 0 9 9 0 9 0 17 9 0 0 9 0 0 0 % N
% Pro: 0 0 0 0 34 0 59 0 0 0 9 0 50 0 0 % P
% Gln: 9 25 34 9 0 0 0 9 9 0 50 9 0 50 0 % Q
% Arg: 0 9 25 0 0 9 0 9 50 9 0 0 0 0 9 % R
% Ser: 0 9 0 0 9 0 0 25 0 0 0 9 17 0 17 % S
% Thr: 9 0 0 0 9 0 0 0 0 17 0 0 0 17 0 % T
% Val: 25 0 0 17 0 0 17 0 0 0 9 9 9 0 0 % V
% Trp: 0 17 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 9 0 0 9 0 0 0 9 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _