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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
NR2E3
All Species:
4.24
Human Site:
S145
Identified Species:
9.33
UniProt:
Q9Y5X4
Number Species:
10
Phosphosite Substitution
Charge Score:
0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9Y5X4
NP_055064.1
410
44692
S145
N
T
E
S
R
P
E
S
L
V
A
P
P
A
P
Chimpanzee
Pan troglodytes
XP_001175025
402
43746
S137
N
T
E
P
R
P
E
S
L
V
A
P
P
A
P
Rhesus Macaque
Macaca mulatta
XP_001089693
448
48652
P183
S
N
E
P
R
P
E
P
L
V
A
T
P
T
P
Dog
Lupus familis
XP_532253
385
42541
A116
G
H
K
E
E
N
G
A
A
A
H
F
P
S
A
Cat
Felis silvestris
Mouse
Mus musculus
Q9QXZ7
395
43158
A121
E
R
Q
P
R
S
M
A
Q
V
H
L
D
A
M
Rat
Rattus norvegicus
O09018
414
45583
C131
D
Q
H
H
R
N
Q
C
Q
Y
C
R
L
K
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q91379
385
42465
G116
G
H
K
E
E
S
S
G
A
P
H
F
P
A
T
Frog
Xenopus laevis
P70052
386
42956
Q118
K
E
V
N
G
S
T
Q
H
F
S
S
T
A
L
Zebra Danio
Brachydanio rerio
Q06725
411
45463
C128
D
Q
H
H
R
N
Q
C
Q
Y
C
R
L
K
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P16375
543
57969
C200
D
S
K
Q
N
I
E
C
V
V
C
G
D
K
S
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_780706
421
46399
E131
V
T
T
A
E
P
H
E
L
A
A
S
P
L
T
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
96.8
85.9
43.6
N.A.
86.3
28.9
N.A.
N.A.
42.9
42.6
27.7
N.A.
27
N.A.
N.A.
61
Protein Similarity:
100
97
86.3
59.7
N.A.
91.2
44.2
N.A.
N.A.
59.2
58.7
43
N.A.
41
N.A.
N.A.
71
P-Site Identity:
100
93.3
60
6.6
N.A.
20
6.6
N.A.
N.A.
13.3
6.6
6.6
N.A.
13.3
N.A.
N.A.
33.3
P-Site Similarity:
100
93.3
66.6
26.6
N.A.
33.3
20
N.A.
N.A.
20
20
20
N.A.
40
N.A.
N.A.
40
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
10
0
0
0
19
19
19
37
0
0
46
10
% A
% Cys:
0
0
0
0
0
0
0
28
0
0
28
0
0
0
0
% C
% Asp:
28
0
0
0
0
0
0
0
0
0
0
0
19
0
0
% D
% Glu:
10
10
28
19
28
0
37
10
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
10
0
19
0
0
0
% F
% Gly:
19
0
0
0
10
0
10
10
0
0
0
10
0
0
0
% G
% His:
0
19
19
19
0
0
10
0
10
0
28
0
0
0
0
% H
% Ile:
0
0
0
0
0
10
0
0
0
0
0
0
0
0
0
% I
% Lys:
10
0
28
0
0
0
0
0
0
0
0
0
0
28
19
% K
% Leu:
0
0
0
0
0
0
0
0
37
0
0
10
19
10
10
% L
% Met:
0
0
0
0
0
0
10
0
0
0
0
0
0
0
10
% M
% Asn:
19
10
0
10
10
28
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
28
0
37
0
10
0
10
0
19
55
0
28
% P
% Gln:
0
19
10
10
0
0
19
10
28
0
0
0
0
0
0
% Q
% Arg:
0
10
0
0
55
0
0
0
0
0
0
19
0
0
0
% R
% Ser:
10
10
0
10
0
28
10
19
0
0
10
19
0
10
10
% S
% Thr:
0
28
10
0
0
0
10
0
0
0
0
10
10
10
19
% T
% Val:
10
0
10
0
0
0
0
0
10
46
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
19
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _