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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
NR2E3
All Species:
13.33
Human Site:
T306
Identified Species:
29.33
UniProt:
Q9Y5X4
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.3
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9Y5X4
NP_055064.1
410
44692
T306
E
T
R
V
L
Q
E
T
I
S
R
F
R
A
L
Chimpanzee
Pan troglodytes
XP_001175025
402
43746
T298
E
T
R
V
L
R
E
T
I
S
R
F
R
A
L
Rhesus Macaque
Macaca mulatta
XP_001089693
448
48652
T344
E
T
R
V
L
R
E
T
I
S
R
F
R
A
L
Dog
Lupus familis
XP_532253
385
42541
R276
Q
E
V
V
A
R
F
R
Q
L
R
L
D
A
T
Cat
Felis silvestris
Mouse
Mus musculus
Q9QXZ7
395
43158
T291
E
T
R
F
L
Q
E
T
I
S
R
F
R
A
L
Rat
Rattus norvegicus
O09018
414
45583
Q298
H
I
R
I
F
Q
E
Q
V
E
K
L
K
A
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q91379
385
42465
R276
Q
E
V
V
A
R
F
R
Q
L
R
L
D
A
T
Frog
Xenopus laevis
P70052
386
42956
R276
Q
D
V
V
S
R
F
R
Q
L
R
L
D
A
T
Zebra Danio
Brachydanio rerio
Q06725
411
45463
Q295
H
I
R
I
F
Q
E
Q
V
E
K
L
K
A
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P16375
543
57969
Q427
H
I
R
I
F
Q
E
Q
V
E
K
L
K
A
L
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_780706
421
46399
I317
D
I
R
L
L
Q
E
I
M
S
R
F
R
G
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
96.8
85.9
43.6
N.A.
86.3
28.9
N.A.
N.A.
42.9
42.6
27.7
N.A.
27
N.A.
N.A.
61
Protein Similarity:
100
97
86.3
59.7
N.A.
91.2
44.2
N.A.
N.A.
59.2
58.7
43
N.A.
41
N.A.
N.A.
71
P-Site Identity:
100
93.3
93.3
20
N.A.
93.3
33.3
N.A.
N.A.
20
20
33.3
N.A.
33.3
N.A.
N.A.
60
P-Site Similarity:
100
100
100
33.3
N.A.
93.3
60
N.A.
N.A.
33.3
33.3
60
N.A.
60
N.A.
N.A.
80
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
19
0
0
0
0
0
0
0
0
91
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
10
10
0
0
0
0
0
0
0
0
0
0
28
0
0
% D
% Glu:
37
19
0
0
0
0
73
0
0
28
0
0
0
0
0
% E
% Phe:
0
0
0
10
28
0
28
0
0
0
0
46
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
0
% G
% His:
28
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
37
0
28
0
0
0
10
37
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
28
0
28
0
0
% K
% Leu:
0
0
0
10
46
0
0
0
0
28
0
55
0
0
73
% L
% Met:
0
0
0
0
0
0
0
0
10
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
28
0
0
0
0
55
0
28
28
0
0
0
0
0
0
% Q
% Arg:
0
0
73
0
0
46
0
28
0
0
73
0
46
0
0
% R
% Ser:
0
0
0
0
10
0
0
0
0
46
0
0
0
0
0
% S
% Thr:
0
37
0
0
0
0
0
37
0
0
0
0
0
0
28
% T
% Val:
0
0
28
55
0
0
0
0
28
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _