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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
NPFFR2
All Species:
5.76
Human Site:
S500
Identified Species:
11.52
UniProt:
Q9Y5X5
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9Y5X5
NP_001138228.1
522
60270
S500
E
T
L
L
Y
R
K
S
A
E
K
P
Q
Q
E
Chimpanzee
Pan troglodytes
XP_001158763
522
60320
S500
E
N
L
L
Y
R
K
S
A
E
K
P
Q
Q
E
Rhesus Macaque
Macaca mulatta
Q9GK74
381
42711
K361
S
V
T
F
K
A
K
K
N
L
E
V
R
K
N
Dog
Lupus familis
XP_851935
470
51517
G450
G
G
R
V
A
H
H
G
S
A
G
E
G
P
G
Cat
Felis silvestris
Mouse
Mus musculus
Q924H0
417
47431
D397
L
G
C
G
K
S
A
D
N
P
T
Q
E
S
L
Rat
Rattus norvegicus
Q9EQD2
417
47692
D397
L
G
C
R
K
S
A
D
N
P
T
Q
E
S
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511746
312
35071
S292
R
L
L
R
S
G
E
S
A
L
N
E
P
E
L
Chicken
Gallus gallus
Q9DDN6
385
43491
K365
S
A
A
F
K
A
R
K
K
L
E
A
K
K
S
Frog
Xenopus laevis
P34992
366
42234
A346
E
D
D
Y
E
T
I
A
M
S
T
M
H
T
D
Zebra Danio
Brachydanio rerio
NP_001098579
422
48060
Q402
R
M
N
H
I
N
E
Q
D
L
V
M
E
D
L
Tiger Blowfish
Takifugu rubipres
NP_001092118
426
48303
L406
N
H
I
A
E
Q
D
L
I
M
E
D
L
E
K
Fruit Fly
Dros. melanogaster
P25931
464
53506
K444
T
Y
I
S
A
R
R
K
P
R
A
T
S
L
R
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.6
27
43
N.A.
63
63.4
N.A.
33.5
25.6
24.8
51.9
52.8
23.9
N.A.
N.A.
N.A.
Protein Similarity:
100
99.2
44.4
60.3
N.A.
70.6
70.6
N.A.
44.2
43.6
40.4
63.4
64.1
43.8
N.A.
N.A.
N.A.
P-Site Identity:
100
93.3
6.6
0
N.A.
0
0
N.A.
20
0
6.6
0
0
6.6
N.A.
N.A.
N.A.
P-Site Similarity:
100
93.3
26.6
13.3
N.A.
6.6
6.6
N.A.
33.3
26.6
20
13.3
33.3
20
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
9
9
9
17
17
17
9
25
9
9
9
0
0
0
% A
% Cys:
0
0
17
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
9
9
0
0
0
9
17
9
0
0
9
0
9
9
% D
% Glu:
25
0
0
0
17
0
17
0
0
17
25
17
25
17
17
% E
% Phe:
0
0
0
17
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
9
25
0
9
0
9
0
9
0
0
9
0
9
0
9
% G
% His:
0
9
0
9
0
9
9
0
0
0
0
0
9
0
0
% H
% Ile:
0
0
17
0
9
0
9
0
9
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
34
0
25
25
9
0
17
0
9
17
9
% K
% Leu:
17
9
25
17
0
0
0
9
0
34
0
0
9
9
34
% L
% Met:
0
9
0
0
0
0
0
0
9
9
0
17
0
0
0
% M
% Asn:
9
9
9
0
0
9
0
0
25
0
9
0
0
0
9
% N
% Pro:
0
0
0
0
0
0
0
0
9
17
0
17
9
9
0
% P
% Gln:
0
0
0
0
0
9
0
9
0
0
0
17
17
17
0
% Q
% Arg:
17
0
9
17
0
25
17
0
0
9
0
0
9
0
9
% R
% Ser:
17
0
0
9
9
17
0
25
9
9
0
0
9
17
9
% S
% Thr:
9
9
9
0
0
9
0
0
0
0
25
9
0
9
0
% T
% Val:
0
9
0
9
0
0
0
0
0
0
9
9
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
9
0
9
17
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _