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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: GPR45 All Species: 12.73
Human Site: S19 Identified Species: 25.45
UniProt: Q9Y5Y3 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0.18
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9Y5Y3 NP_009158.3 372 41967 S19 T Y L L L N T S N A S D S G S
Chimpanzee Pan troglodytes XP_515672 372 41944 S19 P Y L L L N T S N A S D S G S
Rhesus Macaque Macaca mulatta O97666 380 42588 S26 C E Y T D W K S S G A L I P A
Dog Lupus familis XP_538442 372 41845 S19 Q D L L L N G S N V S D S G V
Cat Felis silvestris
Mouse Mus musculus Q9EQQ4 373 42340 S19 E H L L L N V S N T L D P G D
Rat Rattus norvegicus P32305 448 49818 N69 T W D A P P D N V S G C G E Q
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001511019 419 47113 A66 P V I N G T S A P S P S E V F
Chicken Gallus gallus O13076 340 37753
Frog Xenopus laevis P79945 372 42235 A19 M L P N L S I A T A P L D L R
Zebra Danio Brachydanio rerio XP_001335533 375 41755 T20 G L L E P T E T E M Q E A D T
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P41596 511 56152 D128 W T N A S E M D T I V G E E P
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_782049 394 44278 E45 S T M S L G N E S N T M Q P E
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.7 21.5 88.9 N.A. 88.7 23.8 N.A. 50.1 23.6 70.4 63.2 N.A. 21.9 N.A. N.A. 48.7
Protein Similarity: 100 99.7 39.7 93 N.A. 93.3 40.8 N.A. 66.5 42.7 82.8 78.4 N.A. 37.1 N.A. N.A. 65.4
P-Site Identity: 100 93.3 6.6 66.6 N.A. 53.3 6.6 N.A. 0 0 13.3 6.6 N.A. 0 N.A. N.A. 6.6
P-Site Similarity: 100 93.3 26.6 66.6 N.A. 60 26.6 N.A. 26.6 0 26.6 33.3 N.A. 0 N.A. N.A. 33.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 17 0 0 0 17 0 25 9 0 9 0 9 % A
% Cys: 9 0 0 0 0 0 0 0 0 0 0 9 0 0 0 % C
% Asp: 0 9 9 0 9 0 9 9 0 0 0 34 9 9 9 % D
% Glu: 9 9 0 9 0 9 9 9 9 0 0 9 17 17 9 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9 % F
% Gly: 9 0 0 0 9 9 9 0 0 9 9 9 9 34 0 % G
% His: 0 9 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 9 0 0 0 9 0 0 9 0 0 9 0 0 % I
% Lys: 0 0 0 0 0 0 9 0 0 0 0 0 0 0 0 % K
% Leu: 0 17 42 34 50 0 0 0 0 0 9 17 0 9 0 % L
% Met: 9 0 9 0 0 0 9 0 0 9 0 9 0 0 0 % M
% Asn: 0 0 9 17 0 34 9 9 34 9 0 0 0 0 0 % N
% Pro: 17 0 9 0 17 9 0 0 9 0 17 0 9 17 9 % P
% Gln: 9 0 0 0 0 0 0 0 0 0 9 0 9 0 9 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9 % R
% Ser: 9 0 0 9 9 9 9 42 17 17 25 9 25 0 17 % S
% Thr: 17 17 0 9 0 17 17 9 17 9 9 0 0 0 9 % T
% Val: 0 9 0 0 0 0 9 0 9 9 9 0 0 9 9 % V
% Trp: 9 9 0 0 0 9 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 17 9 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _