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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
GPR45
All Species:
11.82
Human Site:
S233
Identified Species:
23.64
UniProt:
Q9Y5Y3
Number Species:
11
Phosphosite Substitution
Charge Score:
0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9Y5Y3
NP_009158.3
372
41967
S233
A
V
R
V
H
N
Q
S
D
S
L
D
L
R
Q
Chimpanzee
Pan troglodytes
XP_515672
372
41944
S233
A
V
R
V
H
N
Q
S
D
S
L
D
L
R
Q
Rhesus Macaque
Macaca mulatta
O97666
380
42588
G239
F
R
K
E
R
I
E
G
L
R
K
R
R
R
L
Dog
Lupus familis
XP_538442
372
41845
S233
A
I
R
V
H
N
Q
S
D
S
L
D
L
R
Q
Cat
Felis silvestris
Mouse
Mus musculus
Q9EQQ4
373
42340
D234
V
R
V
H
N
Q
S
D
S
L
D
L
R
Q
L
Rat
Rattus norvegicus
P32305
448
49818
V296
V
I
S
L
N
G
V
V
K
L
Q
K
E
V
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511019
419
47113
P280
A
V
R
I
H
N
Y
P
D
G
I
C
L
S
Q
Chicken
Gallus gallus
O13076
340
37753
V208
I
Y
I
K
I
F
M
V
A
C
K
Q
L
H
Q
Frog
Xenopus laevis
P79945
372
42235
A233
A
V
R
I
H
T
H
A
D
S
L
C
L
S
Q
Zebra Danio
Brachydanio rerio
XP_001335533
375
41755
S235
L
R
I
H
N
H
T
S
E
G
S
V
A
I
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P41596
511
56152
Y359
E
V
A
E
K
Q
R
Y
K
S
I
R
R
P
K
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_782049
394
44278
P260
S
L
R
I
Q
N
H
P
E
S
L
S
I
S
Q
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.7
21.5
88.9
N.A.
88.7
23.8
N.A.
50.1
23.6
70.4
63.2
N.A.
21.9
N.A.
N.A.
48.7
Protein Similarity:
100
99.7
39.7
93
N.A.
93.3
40.8
N.A.
66.5
42.7
82.8
78.4
N.A.
37.1
N.A.
N.A.
65.4
P-Site Identity:
100
100
6.6
93.3
N.A.
0
0
N.A.
53.3
13.3
60
6.6
N.A.
13.3
N.A.
N.A.
33.3
P-Site Similarity:
100
100
20
100
N.A.
13.3
26.6
N.A.
66.6
13.3
73.3
26.6
N.A.
33.3
N.A.
N.A.
66.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
42
0
9
0
0
0
0
9
9
0
0
0
9
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
9
0
17
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
9
42
0
9
25
0
0
0
% D
% Glu:
9
0
0
17
0
0
9
0
17
0
0
0
9
0
9
% E
% Phe:
9
0
0
0
0
9
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
9
0
9
0
17
0
0
0
0
0
% G
% His:
0
0
0
17
42
9
17
0
0
0
0
0
0
9
0
% H
% Ile:
9
17
17
25
9
9
0
0
0
0
17
0
9
9
0
% I
% Lys:
0
0
9
9
9
0
0
0
17
0
17
9
0
0
9
% K
% Leu:
9
9
0
9
0
0
0
0
9
17
42
9
50
0
17
% L
% Met:
0
0
0
0
0
0
9
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
25
42
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
17
0
0
0
0
0
9
0
% P
% Gln:
0
0
0
0
9
17
25
0
0
0
9
9
0
9
59
% Q
% Arg:
0
25
50
0
9
0
9
0
0
9
0
17
25
34
0
% R
% Ser:
9
0
9
0
0
0
9
34
9
50
9
9
0
25
9
% S
% Thr:
0
0
0
0
0
9
9
0
0
0
0
0
0
0
0
% T
% Val:
17
42
9
25
0
0
9
17
0
0
0
9
0
9
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
9
0
0
0
0
9
9
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _