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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
GPR45
All Species:
21.52
Human Site:
Y297
Identified Species:
43.03
UniProt:
Q9Y5Y3
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9Y5Y3
NP_009158.3
372
41967
Y297
S
V
F
S
Q
R
F
Y
C
G
S
S
F
Y
A
Chimpanzee
Pan troglodytes
XP_515672
372
41944
Y297
S
V
F
S
Q
R
F
Y
C
G
S
S
F
Y
A
Rhesus Macaque
Macaca mulatta
O97666
380
42588
C303
C
I
S
Y
V
N
S
C
L
N
P
F
L
Y
A
Dog
Lupus familis
XP_538442
372
41845
Y297
S
V
F
S
R
G
F
Y
C
S
S
S
F
Y
T
Cat
Felis silvestris
Mouse
Mus musculus
Q9EQQ4
373
42340
Y298
S
A
F
S
R
R
F
Y
Y
S
A
S
F
Y
T
Rat
Rattus norvegicus
P32305
448
49818
S360
R
P
F
I
C
G
T
S
C
S
C
I
P
L
W
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511019
419
47113
Y344
A
T
F
D
D
R
F
Y
S
G
R
D
F
F
E
Chicken
Gallus gallus
O13076
340
37753
M272
K
S
K
P
E
W
V
M
Y
V
A
I
I
L
S
Frog
Xenopus laevis
P79945
372
42235
Y297
S
V
F
S
R
T
F
Y
Y
S
S
S
F
Y
S
Zebra Danio
Brachydanio rerio
XP_001335533
375
41755
Y299
S
V
F
S
R
R
F
Y
L
S
P
A
F
Y
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P41596
511
56152
I423
A
A
F
C
K
T
C
I
G
G
Q
T
F
K
I
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_782049
394
44278
G324
Y
H
F
S
V
R
T
G
G
D
V
M
H
T
I
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.7
21.5
88.9
N.A.
88.7
23.8
N.A.
50.1
23.6
70.4
63.2
N.A.
21.9
N.A.
N.A.
48.7
Protein Similarity:
100
99.7
39.7
93
N.A.
93.3
40.8
N.A.
66.5
42.7
82.8
78.4
N.A.
37.1
N.A.
N.A.
65.4
P-Site Identity:
100
100
13.3
73.3
N.A.
60
13.3
N.A.
40
0
66.6
60
N.A.
20
N.A.
N.A.
20
P-Site Similarity:
100
100
20
80
N.A.
73.3
13.3
N.A.
53.3
20
80
73.3
N.A.
40
N.A.
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
17
17
0
0
0
0
0
0
0
0
17
9
0
0
25
% A
% Cys:
9
0
0
9
9
0
9
9
34
0
9
0
0
0
0
% C
% Asp:
0
0
0
9
9
0
0
0
0
9
0
9
0
0
0
% D
% Glu:
0
0
0
0
9
0
0
0
0
0
0
0
0
0
9
% E
% Phe:
0
0
84
0
0
0
59
0
0
0
0
9
67
9
0
% F
% Gly:
0
0
0
0
0
17
0
9
17
34
0
0
0
0
0
% G
% His:
0
9
0
0
0
0
0
0
0
0
0
0
9
0
0
% H
% Ile:
0
9
0
9
0
0
0
9
0
0
0
17
9
0
17
% I
% Lys:
9
0
9
0
9
0
0
0
0
0
0
0
0
9
0
% K
% Leu:
0
0
0
0
0
0
0
0
17
0
0
0
9
17
0
% L
% Met:
0
0
0
0
0
0
0
9
0
0
0
9
0
0
0
% M
% Asn:
0
0
0
0
0
9
0
0
0
9
0
0
0
0
0
% N
% Pro:
0
9
0
9
0
0
0
0
0
0
17
0
9
0
9
% P
% Gln:
0
0
0
0
17
0
0
0
0
0
9
0
0
0
0
% Q
% Arg:
9
0
0
0
34
50
0
0
0
0
9
0
0
0
0
% R
% Ser:
50
9
9
59
0
0
9
9
9
42
34
42
0
0
17
% S
% Thr:
0
9
0
0
0
17
17
0
0
0
0
9
0
9
17
% T
% Val:
0
42
0
0
17
0
9
0
0
9
9
0
0
0
0
% V
% Trp:
0
0
0
0
0
9
0
0
0
0
0
0
0
0
9
% W
% Tyr:
9
0
0
9
0
0
0
59
25
0
0
0
0
59
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _