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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
GPR44
All Species:
3.64
Human Site:
S376
Identified Species:
10
UniProt:
Q9Y5Y4
Number Species:
8
Phosphosite Substitution
Charge Score:
-0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9Y5Y4
NP_004769
395
43268
S376
L
L
G
W
L
L
G
S
C
A
A
S
P
Q
T
Chimpanzee
Pan troglodytes
P79242
348
38556
N330
S
E
D
S
A
P
T
N
D
T
A
A
N
C
A
Rhesus Macaque
Macaca mulatta
P79190
348
38438
N330
S
E
D
S
A
P
T
N
D
T
A
A
S
C
A
Dog
Lupus familis
XP_543447
365
41167
S347
T
V
H
S
S
Y
P
S
H
R
S
F
T
K
M
Cat
Felis silvestris
Mouse
Mus musculus
Q9Z2J6
382
42931
P364
D
R
I
P
Q
L
R
P
T
R
L
I
G
W
M
Rat
Rattus norvegicus
O35786
371
41704
K353
P
S
H
R
S
F
T
K
M
S
S
L
I
E
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509413
368
41356
K350
L
S
H
R
G
V
T
K
M
S
S
M
N
E
R
Chicken
Gallus gallus
XP_425239
361
40353
S343
T
E
E
S
M
L
G
S
L
S
S
R
R
K
S
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
P0C7U4
361
41032
E338
L
S
L
R
R
V
F
E
R
A
F
S
E
E
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
30.3
29.8
29.3
N.A.
77.4
29.3
N.A.
30.8
31.8
N.A.
30.8
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
48.8
50.1
48.6
N.A.
84.8
48.8
N.A.
49.6
51.9
N.A.
49.8
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
6.6
6.6
6.6
N.A.
6.6
0
N.A.
6.6
20
N.A.
20
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
20
20
26.6
N.A.
6.6
20
N.A.
33.3
53.3
N.A.
33.3
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
23
0
0
0
0
23
34
23
0
0
23
% A
% Cys:
0
0
0
0
0
0
0
0
12
0
0
0
0
23
0
% C
% Asp:
12
0
23
0
0
0
0
0
23
0
0
0
0
0
0
% D
% Glu:
0
34
12
0
0
0
0
12
0
0
0
0
12
34
0
% E
% Phe:
0
0
0
0
0
12
12
0
0
0
12
12
0
0
0
% F
% Gly:
0
0
12
0
12
0
23
0
0
0
0
0
12
0
12
% G
% His:
0
0
34
0
0
0
0
0
12
0
0
0
0
0
0
% H
% Ile:
0
0
12
0
0
0
0
0
0
0
0
12
12
0
0
% I
% Lys:
0
0
0
0
0
0
0
23
0
0
0
0
0
23
12
% K
% Leu:
34
12
12
0
12
34
0
0
12
0
12
12
0
0
0
% L
% Met:
0
0
0
0
12
0
0
0
23
0
0
12
0
0
23
% M
% Asn:
0
0
0
0
0
0
0
23
0
0
0
0
23
0
0
% N
% Pro:
12
0
0
12
0
23
12
12
0
0
0
0
12
0
0
% P
% Gln:
0
0
0
0
12
0
0
0
0
0
0
0
0
12
0
% Q
% Arg:
0
12
0
34
12
0
12
0
12
23
0
12
12
0
12
% R
% Ser:
23
34
0
45
23
0
0
34
0
34
45
23
12
0
12
% S
% Thr:
23
0
0
0
0
0
45
0
12
23
0
0
12
0
12
% T
% Val:
0
12
0
0
0
23
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
12
0
0
0
0
0
0
0
0
0
12
0
% W
% Tyr:
0
0
0
0
0
12
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _