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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
LYVE1
All Species:
21.21
Human Site:
T280
Identified Species:
51.85
UniProt:
Q9Y5Y7
Number Species:
9
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9Y5Y7
NP_006682.2
322
35213
T280
Q
Q
K
E
M
I
E
T
K
V
V
K
E
E
K
Chimpanzee
Pan troglodytes
XP_508283
322
35252
T280
Q
Q
K
E
M
I
E
T
I
V
V
K
E
E
K
Rhesus Macaque
Macaca mulatta
XP_001100103
321
35195
T279
Q
Q
K
E
M
I
E
T
K
V
V
K
E
E
K
Dog
Lupus familis
XP_854301
324
35729
T282
Q
Q
K
E
M
I
E
T
K
V
V
K
E
E
K
Cat
Felis silvestris
Mouse
Mus musculus
Q8BHC0
318
34555
T276
Q
Q
K
E
M
I
E
T
K
V
V
K
E
E
K
Rat
Rattus norvegicus
P26051
503
55927
G448
K
K
L
V
I
N
S
G
N
G
T
V
E
D
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513902
176
19190
K135
Q
K
E
V
I
E
T
K
T
V
K
E
A
K
G
Chicken
Gallus gallus
XP_420971
308
33716
T266
Q
K
K
E
V
V
E
T
T
A
L
K
D
T
A
Frog
Xenopus laevis
NP_001085302
278
31119
Q237
E
D
G
E
I
M
E
Q
N
G
D
N
V
K
S
Zebra Danio
Brachydanio rerio
XP_689109
328
36721
E281
Q
V
E
D
K
N
Q
E
E
Q
M
E
E
K
N
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.4
94
74.6
N.A.
68.9
21.6
N.A.
30.7
38.2
25.4
20.4
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
98.7
95.6
83.6
N.A.
78.5
35.7
N.A.
39.1
55.5
42.8
41.1
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
93.3
100
100
N.A.
100
6.6
N.A.
13.3
40
13.3
13.3
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
93.3
100
100
N.A.
100
40
N.A.
46.6
73.3
40
60
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
10
0
0
10
0
10
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
10
0
10
0
0
0
0
0
0
10
0
10
10
0
% D
% Glu:
10
0
20
70
0
10
70
10
10
0
0
20
70
50
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
10
0
0
0
0
10
0
20
0
0
0
0
10
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
30
50
0
0
10
0
0
0
0
0
0
% I
% Lys:
10
30
60
0
10
0
0
10
40
0
10
60
0
30
50
% K
% Leu:
0
0
10
0
0
0
0
0
0
0
10
0
0
0
0
% L
% Met:
0
0
0
0
50
10
0
0
0
0
10
0
0
0
0
% M
% Asn:
0
0
0
0
0
20
0
0
20
0
0
10
0
0
10
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
80
50
0
0
0
0
10
10
0
10
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% R
% Ser:
0
0
0
0
0
0
10
0
0
0
0
0
0
0
10
% S
% Thr:
0
0
0
0
0
0
10
60
20
0
10
0
0
10
0
% T
% Val:
0
10
0
20
10
10
0
0
0
60
50
10
10
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _