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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SCN10A All Species: 5.76
Human Site: S956 Identified Species: 14.07
UniProt: Q9Y5Y9 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9Y5Y9 NP_006505.2 1956 220626 S956 V K L P L S S S K A E N H I A
Chimpanzee Pan troglodytes XP_516372 1956 220469 S956 V K L P L S S S K A E N H V A
Rhesus Macaque Macaca mulatta XP_001100281 1957 223189 A987 A F V R K Q K A L D E I K P L
Dog Lupus familis XP_858252 1960 223552 A987 A F V R K Q K A L D E I K P L
Cat Felis silvestris
Mouse Mus musculus Q6QIY3 1958 220533 A957 P P L T S C K A E N H I A T D
Rat Rattus norvegicus Q62968 1956 219714 A957 P P L T S S E A K N H I A T D
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_001232818 2040 231951 G1032 S H P T A E L G K E M E N H K
Frog Xenopus laevis
Zebra Danio Brachydanio rerio Q20JQ7 1784 201644 V869 S S S S M V K V P I A N G E S
Tiger Blowfish Takifugu rubipres Q2XVR7 1892 213080 P889 L G R E P Q K P A E E D P A D
Fruit Fly Dros. melanogaster P35500 2131 239344 S1098 N Q I S D Q P S G E R T N Q I
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.3 57.5 57.5 N.A. 82.2 83 N.A. N.A. 62.5 N.A. 54 54.1 43.1 N.A. N.A. N.A.
Protein Similarity: 100 99.6 72.9 72.5 N.A. 89.2 89.8 N.A. N.A. 75.1 N.A. 68.7 69.1 58.6 N.A. N.A. N.A.
P-Site Identity: 100 93.3 6.6 6.6 N.A. 6.6 20 N.A. N.A. 6.6 N.A. 6.6 6.6 6.6 N.A. N.A. N.A.
P-Site Similarity: 100 100 20 20 N.A. 20 26.6 N.A. N.A. 13.3 N.A. 20 20 26.6 N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 20 0 0 0 10 0 0 40 10 20 10 0 20 10 20 % A
% Cys: 0 0 0 0 0 10 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 10 0 0 0 0 20 0 10 0 0 30 % D
% Glu: 0 0 0 10 0 10 10 0 10 30 50 10 0 10 0 % E
% Phe: 0 20 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 10 0 0 0 0 0 10 10 0 0 0 10 0 0 % G
% His: 0 10 0 0 0 0 0 0 0 0 20 0 20 10 0 % H
% Ile: 0 0 10 0 0 0 0 0 0 10 0 40 0 10 10 % I
% Lys: 0 20 0 0 20 0 50 0 40 0 0 0 20 0 10 % K
% Leu: 10 0 40 0 20 0 10 0 20 0 0 0 0 0 20 % L
% Met: 0 0 0 0 10 0 0 0 0 0 10 0 0 0 0 % M
% Asn: 10 0 0 0 0 0 0 0 0 20 0 30 20 0 0 % N
% Pro: 20 20 10 20 10 0 10 10 10 0 0 0 10 20 0 % P
% Gln: 0 10 0 0 0 40 0 0 0 0 0 0 0 10 0 % Q
% Arg: 0 0 10 20 0 0 0 0 0 0 10 0 0 0 0 % R
% Ser: 20 10 10 20 20 30 20 30 0 0 0 0 0 0 10 % S
% Thr: 0 0 0 30 0 0 0 0 0 0 0 10 0 20 0 % T
% Val: 20 0 20 0 0 10 0 10 0 0 0 0 0 10 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _