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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: HCFC2 All Species: 19.7
Human Site: S120 Identified Species: 33.33
UniProt: Q9Y5Z7 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9Y5Z7 NP_037452.1 792 86779 S120 V K P H P P P S G L P P C P R
Chimpanzee Pan troglodytes XP_509326 792 86791 S120 V K P H P P P S G L P P C P R
Rhesus Macaque Macaca mulatta XP_001097074 792 86781 S120 V K P H P P P S G L P P C P R
Dog Lupus familis XP_532674 790 86251 S120 V K P H P P S S G L P P C P R
Cat Felis silvestris
Mouse Mus musculus Q61191 2045 210519 N130 L K A K T P K N G P P P C P R
Rat Rattus norvegicus Q5RKG2 723 79130 P70 A V R G D I P P G C A A H G F
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001507728 758 83389 N88 H S F S L Y G N K C Y L F G G
Chicken Gallus gallus XP_001234928 787 86020 T121 V K P Q A P S T G S P P C P R
Frog Xenopus laevis NP_001087989 2101 219049 N128 L K A K A P K N G P P P C P R
Zebra Danio Brachydanio rerio NP_001038529 1778 182507 N129 L K P K A P K N G V P P C P R
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9V4C8 1500 160166 S171 M Y P E S P D S G L S P C P R
Honey Bee Apis mellifera XP_624189 1550 166762 N119 L R P R P P E N D P P P C P R
Nematode Worm Caenorhab. elegans NP_501279 782 87341 P90 P Q C C G D V P T P A A A F G
Sea Urchin Strong. purpuratus XP_791039 1216 126587 N119 L K P K T A K N A P P P C P R
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.3 99.4 94.8 N.A. 25.9 82 N.A. 72.5 73.7 25.3 28.7 N.A. 29.5 29.2 39.6 32
Protein Similarity: 100 99.8 99.6 97 N.A. 32 86.2 N.A. 80.8 83.9 31.5 36.3 N.A. 40.2 39.6 56 44.3
P-Site Identity: 100 100 100 93.3 N.A. 53.3 13.3 N.A. 0 66.6 53.3 60 N.A. 60 53.3 0 46.6
P-Site Similarity: 100 100 100 93.3 N.A. 66.6 13.3 N.A. 6.6 73.3 66.6 80 N.A. 66.6 73.3 6.6 60
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 8 0 15 0 22 8 0 0 8 0 15 15 8 0 0 % A
% Cys: 0 0 8 8 0 0 0 0 0 15 0 0 79 0 0 % C
% Asp: 0 0 0 0 8 8 8 0 8 0 0 0 0 0 0 % D
% Glu: 0 0 0 8 0 0 8 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 8 0 0 0 0 0 0 0 0 0 8 8 8 % F
% Gly: 0 0 0 8 8 0 8 0 72 0 0 0 0 15 15 % G
% His: 8 0 0 29 0 0 0 0 0 0 0 0 8 0 0 % H
% Ile: 0 0 0 0 0 8 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 65 0 29 0 0 29 0 8 0 0 0 0 0 0 % K
% Leu: 36 0 0 0 8 0 0 0 0 36 0 8 0 0 0 % L
% Met: 8 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 43 0 0 0 0 0 0 0 % N
% Pro: 8 0 65 0 36 72 29 15 0 36 72 79 0 79 0 % P
% Gln: 0 8 0 8 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 8 8 8 0 0 0 0 0 0 0 0 0 0 79 % R
% Ser: 0 8 0 8 8 0 15 36 0 8 8 0 0 0 0 % S
% Thr: 0 0 0 0 15 0 0 8 8 0 0 0 0 0 0 % T
% Val: 36 8 0 0 0 0 8 0 0 8 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 8 0 0 0 8 0 0 0 0 8 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _