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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HCFC2
All Species:
9.09
Human Site:
S391
Identified Species:
15.38
UniProt:
Q9Y5Z7
Number Species:
13
Phosphosite Substitution
Charge Score:
0.15
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9Y5Z7
NP_037452.1
792
86779
S391
E
G
Y
L
L
Q
L
S
T
D
L
P
Y
Q
A
Chimpanzee
Pan troglodytes
XP_509326
792
86791
S391
E
G
Y
L
L
Q
L
S
T
D
L
P
Y
Q
A
Rhesus Macaque
Macaca mulatta
XP_001097074
792
86781
S391
E
G
Y
L
L
Q
L
S
T
D
L
P
Y
Q
A
Dog
Lupus familis
XP_532674
790
86251
N391
E
G
Y
L
L
Q
L
N
T
D
L
P
Y
Q
A
Cat
Felis silvestris
Mouse
Mus musculus
Q61191
2045
210519
Q398
D
S
Y
L
L
Q
L
Q
K
Y
D
I
P
A
T
Rat
Rattus norvegicus
Q5RKG2
723
79130
Y336
F
W
S
G
R
D
G
Y
K
K
A
L
N
S
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507728
758
83389
D365
N
L
Q
E
V
K
L
D
L
Q
R
Q
A
K
N
Chicken
Gallus gallus
XP_001234928
787
86020
H391
E
G
Y
L
L
Q
L
H
A
D
S
P
V
P
S
Frog
Xenopus laevis
NP_001087989
2101
219049
Q396
D
S
Y
L
L
Q
L
Q
K
Y
D
I
P
A
A
Zebra Danio
Brachydanio rerio
NP_001038529
1778
182507
Q397
D
T
Y
L
L
Q
L
Q
K
Y
D
I
P
A
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9V4C8
1500
160166
Q439
A
A
Y
V
L
Q
I
Q
K
I
E
Q
P
L
N
Honey Bee
Apis mellifera
XP_624189
1550
166762
Q386
Q
Y
Y
I
L
Q
I
Q
K
C
K
P
S
T
T
Nematode Worm
Caenorhab. elegans
NP_501279
782
87341
D356
M
Y
I
W
S
G
R
D
G
Y
R
K
A
W
S
Sea Urchin
Strong. purpuratus
XP_791039
1216
126587
Q387
D
A
Y
L
L
Q
L
Q
K
Y
D
M
P
P
T
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.3
99.4
94.8
N.A.
25.9
82
N.A.
72.5
73.7
25.3
28.7
N.A.
29.5
29.2
39.6
32
Protein Similarity:
100
99.8
99.6
97
N.A.
32
86.2
N.A.
80.8
83.9
31.5
36.3
N.A.
40.2
39.6
56
44.3
P-Site Identity:
100
100
100
93.3
N.A.
33.3
0
N.A.
6.6
60
40
40
N.A.
20
26.6
0
33.3
P-Site Similarity:
100
100
100
100
N.A.
40
0
N.A.
26.6
66.6
46.6
46.6
N.A.
33.3
46.6
6.6
40
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
15
0
0
0
0
0
0
8
0
8
0
15
22
43
% A
% Cys:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% C
% Asp:
29
0
0
0
0
8
0
15
0
36
29
0
0
0
0
% D
% Glu:
36
0
0
8
0
0
0
0
0
0
8
0
0
0
0
% E
% Phe:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
36
0
8
0
8
8
0
8
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% H
% Ile:
0
0
8
8
0
0
15
0
0
8
0
22
0
0
0
% I
% Lys:
0
0
0
0
0
8
0
0
50
8
8
8
0
8
0
% K
% Leu:
0
8
0
65
79
0
72
0
8
0
29
8
0
8
0
% L
% Met:
8
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% M
% Asn:
8
0
0
0
0
0
0
8
0
0
0
0
8
0
15
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
43
36
15
0
% P
% Gln:
8
0
8
0
0
79
0
43
0
8
0
15
0
29
8
% Q
% Arg:
0
0
0
0
8
0
8
0
0
0
15
0
0
0
0
% R
% Ser:
0
15
8
0
8
0
0
22
0
0
8
0
8
8
15
% S
% Thr:
0
8
0
0
0
0
0
0
29
0
0
0
0
8
22
% T
% Val:
0
0
0
8
8
0
0
0
0
0
0
0
8
0
0
% V
% Trp:
0
8
0
8
0
0
0
0
0
0
0
0
0
8
0
% W
% Tyr:
0
15
79
0
0
0
0
8
0
36
0
0
29
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _