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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HCFC2
All Species:
17.88
Human Site:
S401
Identified Species:
30.26
UniProt:
Q9Y5Z7
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9Y5Z7
NP_037452.1
792
86779
S401
L
P
Y
Q
A
A
S
S
D
S
S
A
A
P
N
Chimpanzee
Pan troglodytes
XP_509326
792
86791
S401
L
P
Y
Q
A
A
S
S
D
S
S
A
A
P
N
Rhesus Macaque
Macaca mulatta
XP_001097074
792
86781
S401
L
P
Y
Q
A
A
S
S
D
S
S
A
A
P
N
Dog
Lupus familis
XP_532674
790
86251
S401
L
P
Y
Q
A
A
S
S
D
S
S
A
A
P
N
Cat
Felis silvestris
Mouse
Mus musculus
Q61191
2045
210519
T408
D
I
P
A
T
A
A
T
A
T
S
P
T
P
N
Rat
Rattus norvegicus
Q5RKG2
723
79130
C346
A
L
N
S
Q
V
C
C
K
D
L
W
Y
L
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507728
758
83389
V375
R
Q
A
K
N
N
T
V
P
N
N
V
K
D
P
Chicken
Gallus gallus
XP_001234928
787
86020
G401
S
P
V
P
S
A
A
G
T
P
G
T
G
V
P
Frog
Xenopus laevis
NP_001087989
2101
219049
A406
D
I
P
A
A
A
A
A
M
S
P
A
N
P
V
Zebra Danio
Brachydanio rerio
NP_001038529
1778
182507
A407
D
I
P
A
A
T
A
A
T
S
P
A
L
N
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9V4C8
1500
160166
S449
E
Q
P
L
N
T
S
S
K
L
L
S
N
N
I
Honey Bee
Apis mellifera
XP_624189
1550
166762
T396
K
P
S
T
T
T
G
T
F
P
T
V
S
T
P
Nematode Worm
Caenorhab. elegans
NP_501279
782
87341
V366
R
K
A
W
S
N
Q
V
C
C
R
D
M
W
L
Sea Urchin
Strong. purpuratus
XP_791039
1216
126587
A397
D
M
P
P
T
S
S
A
A
L
S
S
V
G
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.3
99.4
94.8
N.A.
25.9
82
N.A.
72.5
73.7
25.3
28.7
N.A.
29.5
29.2
39.6
32
Protein Similarity:
100
99.8
99.6
97
N.A.
32
86.2
N.A.
80.8
83.9
31.5
36.3
N.A.
40.2
39.6
56
44.3
P-Site Identity:
100
100
100
100
N.A.
26.6
0
N.A.
0
13.3
33.3
20
N.A.
13.3
6.6
0
13.3
P-Site Similarity:
100
100
100
100
N.A.
46.6
6.6
N.A.
26.6
26.6
46.6
33.3
N.A.
20
26.6
6.6
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
15
22
43
50
29
22
15
0
0
43
29
0
8
% A
% Cys:
0
0
0
0
0
0
8
8
8
8
0
0
0
0
0
% C
% Asp:
29
0
0
0
0
0
0
0
29
8
0
8
0
8
8
% D
% Glu:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
8
8
0
0
8
0
8
8
8
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
22
0
0
0
0
0
0
0
0
0
0
0
0
8
% I
% Lys:
8
8
0
8
0
0
0
0
15
0
0
0
8
0
0
% K
% Leu:
29
8
0
8
0
0
0
0
0
15
15
0
8
8
8
% L
% Met:
0
8
0
0
0
0
0
0
8
0
0
0
8
0
0
% M
% Asn:
0
0
8
0
15
15
0
0
0
8
8
0
15
15
36
% N
% Pro:
0
43
36
15
0
0
0
0
8
15
15
8
0
43
22
% P
% Gln:
0
15
0
29
8
0
8
0
0
0
0
0
0
0
0
% Q
% Arg:
15
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% R
% Ser:
8
0
8
8
15
8
43
36
0
43
43
15
8
0
0
% S
% Thr:
0
0
0
8
22
22
8
15
15
8
8
8
8
8
0
% T
% Val:
0
0
8
0
0
8
0
15
0
0
0
15
8
8
8
% V
% Trp:
0
0
0
8
0
0
0
0
0
0
0
8
0
8
0
% W
% Tyr:
0
0
29
0
0
0
0
0
0
0
0
0
8
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _