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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HCFC2
All Species:
16.06
Human Site:
S477
Identified Species:
27.18
UniProt:
Q9Y5Z7
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9Y5Z7
NP_037452.1
792
86779
S477
S
N
A
S
N
H
N
S
H
V
V
D
M
L
R
Chimpanzee
Pan troglodytes
XP_509326
792
86791
S477
S
N
A
S
N
H
N
S
H
V
V
D
M
L
R
Rhesus Macaque
Macaca mulatta
XP_001097074
792
86781
S477
S
N
A
S
N
H
N
S
H
V
V
D
M
L
R
Dog
Lupus familis
XP_532674
790
86251
S475
A
N
A
S
N
H
N
S
C
V
V
D
V
L
R
Cat
Felis silvestris
Mouse
Mus musculus
Q61191
2045
210519
P1490
T
S
V
S
S
T
L
P
R
A
V
T
T
V
T
Rat
Rattus norvegicus
Q5RKG2
723
79130
G420
R
T
D
P
H
R
Q
G
S
N
S
I
L
H
N
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507728
758
83389
L450
T
S
A
N
V
G
E
L
F
Y
L
D
L
R
A
Chicken
Gallus gallus
XP_001234928
787
86020
C475
P
V
C
T
S
K
T
C
S
V
V
D
E
L
R
Frog
Xenopus laevis
NP_001087989
2101
219049
S1288
N
T
P
T
T
A
R
S
N
I
G
S
G
Q
T
Zebra Danio
Brachydanio rerio
NP_001038529
1778
182507
N1089
T
H
E
T
G
T
T
N
T
A
T
T
A
S
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9V4C8
1500
160166
S529
S
Q
P
S
S
P
A
S
R
A
D
K
D
P
L
Honey Bee
Apis mellifera
XP_624189
1550
166762
Q741
T
N
H
V
T
N
Q
Q
G
V
K
M
I
V
V
Nematode Worm
Caenorhab. elegans
NP_501279
782
87341
P440
R
K
Q
P
S
I
V
P
P
S
Q
K
E
T
E
Sea Urchin
Strong. purpuratus
XP_791039
1216
126587
P750
T
S
Q
G
L
T
T
P
L
T
I
T
T
T
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.3
99.4
94.8
N.A.
25.9
82
N.A.
72.5
73.7
25.3
28.7
N.A.
29.5
29.2
39.6
32
Protein Similarity:
100
99.8
99.6
97
N.A.
32
86.2
N.A.
80.8
83.9
31.5
36.3
N.A.
40.2
39.6
56
44.3
P-Site Identity:
100
100
100
80
N.A.
13.3
0
N.A.
13.3
33.3
6.6
0
N.A.
20
13.3
0
0
P-Site Similarity:
100
100
100
93.3
N.A.
40
13.3
N.A.
46.6
46.6
33.3
26.6
N.A.
26.6
40
6.6
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
36
0
0
8
8
0
0
22
0
0
8
0
15
% A
% Cys:
0
0
8
0
0
0
0
8
8
0
0
0
0
0
0
% C
% Asp:
0
0
8
0
0
0
0
0
0
0
8
43
8
0
0
% D
% Glu:
0
0
8
0
0
0
8
0
0
0
0
0
15
0
8
% E
% Phe:
0
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% F
% Gly:
0
0
0
8
8
8
0
8
8
0
8
0
8
0
0
% G
% His:
0
8
8
0
8
29
0
0
22
0
0
0
0
8
0
% H
% Ile:
0
0
0
0
0
8
0
0
0
8
8
8
8
0
0
% I
% Lys:
0
8
0
0
0
8
0
0
0
0
8
15
0
0
0
% K
% Leu:
0
0
0
0
8
0
8
8
8
0
8
0
15
36
8
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
8
22
0
0
% M
% Asn:
8
36
0
8
29
8
29
8
8
8
0
0
0
0
8
% N
% Pro:
8
0
15
15
0
8
0
22
8
0
0
0
0
8
0
% P
% Gln:
0
8
15
0
0
0
15
8
0
0
8
0
0
8
0
% Q
% Arg:
15
0
0
0
0
8
8
0
15
0
0
0
0
8
36
% R
% Ser:
29
22
0
43
29
0
0
43
15
8
8
8
0
8
8
% S
% Thr:
36
15
0
22
15
22
22
0
8
8
8
22
15
15
15
% T
% Val:
0
8
8
8
8
0
8
0
0
43
43
0
8
15
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _