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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HCFC2
All Species:
16.36
Human Site:
S514
Identified Species:
27.69
UniProt:
Q9Y5Z7
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9Y5Z7
NP_037452.1
792
86779
S514
V
I
P
E
T
S
V
S
S
T
V
S
S
T
Q
Chimpanzee
Pan troglodytes
XP_509326
792
86791
S514
V
I
P
E
T
S
V
S
S
T
V
S
S
T
Q
Rhesus Macaque
Macaca mulatta
XP_001097074
792
86781
S514
V
I
P
E
T
S
V
S
S
T
V
S
S
T
Q
Dog
Lupus familis
XP_532674
790
86251
S512
V
V
P
E
T
S
V
S
S
S
V
S
S
A
Q
Cat
Felis silvestris
Mouse
Mus musculus
Q61191
2045
210519
Q1527
R
Q
Q
L
P
P
R
Q
L
L
Q
S
A
S
T
Rat
Rattus norvegicus
Q5RKG2
723
79130
R457
L
K
S
K
P
D
S
R
A
A
D
S
S
V
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507728
758
83389
N487
I
K
T
E
P
S
I
N
G
A
I
A
N
D
E
Chicken
Gallus gallus
XP_001234928
787
86020
S512
I
P
D
A
S
V
S
S
T
V
S
S
T
Q
T
Frog
Xenopus laevis
NP_001087989
2101
219049
S1325
S
E
S
N
K
V
P
S
S
S
S
E
A
N
D
Zebra Danio
Brachydanio rerio
NP_001038529
1778
182507
A1126
E
T
G
T
T
N
T
A
T
T
A
S
S
S
M
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9V4C8
1500
160166
V566
V
I
S
S
T
A
A
V
T
G
N
D
T
A
S
Honey Bee
Apis mellifera
XP_624189
1550
166762
I778
G
V
P
K
T
V
T
I
A
T
K
G
S
P
Q
Nematode Worm
Caenorhab. elegans
NP_501279
782
87341
A477
A
P
A
D
P
K
P
A
T
D
E
G
G
L
P
Sea Urchin
Strong. purpuratus
XP_791039
1216
126587
N787
T
S
V
S
P
A
I
N
A
I
M
S
T
T
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.3
99.4
94.8
N.A.
25.9
82
N.A.
72.5
73.7
25.3
28.7
N.A.
29.5
29.2
39.6
32
Protein Similarity:
100
99.8
99.6
97
N.A.
32
86.2
N.A.
80.8
83.9
31.5
36.3
N.A.
40.2
39.6
56
44.3
P-Site Identity:
100
100
100
80
N.A.
6.6
13.3
N.A.
13.3
13.3
13.3
26.6
N.A.
20
33.3
0
13.3
P-Site Similarity:
100
100
100
93.3
N.A.
20
33.3
N.A.
60
40
26.6
53.3
N.A.
40
53.3
20
53.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
8
8
0
15
8
15
22
15
8
8
15
15
15
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
8
8
0
8
0
0
0
8
8
8
0
8
8
% D
% Glu:
8
8
0
36
0
0
0
0
0
0
8
8
0
0
8
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
8
0
8
0
0
0
0
0
8
8
0
15
8
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
15
29
0
0
0
0
15
8
0
8
8
0
0
0
0
% I
% Lys:
0
15
0
15
8
8
0
0
0
0
8
0
0
0
0
% K
% Leu:
8
0
0
8
0
0
0
0
8
8
0
0
0
8
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
8
% M
% Asn:
0
0
0
8
0
8
0
15
0
0
8
0
8
8
0
% N
% Pro:
0
15
36
0
36
8
15
0
0
0
0
0
0
8
8
% P
% Gln:
0
8
8
0
0
0
0
8
0
0
8
0
0
8
36
% Q
% Arg:
8
0
0
0
0
0
8
8
0
0
0
0
0
0
0
% R
% Ser:
8
8
22
15
8
36
15
43
36
15
15
65
50
15
8
% S
% Thr:
8
8
8
8
50
0
15
0
29
36
0
0
22
29
15
% T
% Val:
36
15
8
0
0
22
29
8
0
8
29
0
0
8
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _