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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HCFC2
All Species:
19.09
Human Site:
S554
Identified Species:
32.31
UniProt:
Q9Y5Z7
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9Y5Z7
NP_037452.1
792
86779
S554
L
T
T
F
S
T
K
S
E
V
D
E
T
Y
A
Chimpanzee
Pan troglodytes
XP_509326
792
86791
S554
L
T
T
F
S
T
K
S
E
V
D
E
T
Y
A
Rhesus Macaque
Macaca mulatta
XP_001097074
792
86781
S554
L
T
T
F
S
T
K
S
E
V
D
E
T
Y
A
Dog
Lupus familis
XP_532674
790
86251
S552
L
T
T
F
S
T
K
S
E
V
D
E
T
C
A
Cat
Felis silvestris
Mouse
Mus musculus
Q61191
2045
210519
G1567
S
T
G
D
P
S
S
G
Q
E
P
T
T
S
A
Rat
Rattus norvegicus
Q5RKG2
723
79130
A497
D
E
I
C
A
L
P
A
T
K
I
S
R
V
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507728
758
83389
L527
T
N
D
C
T
I
P
L
S
K
K
V
P
L
K
Chicken
Gallus gallus
XP_001234928
787
86020
E552
T
T
F
N
S
K
S
E
A
A
E
T
A
Y
F
Frog
Xenopus laevis
NP_001087989
2101
219049
S1365
N
T
S
T
T
S
R
S
N
I
G
A
E
Q
A
Zebra Danio
Brachydanio rerio
NP_001038529
1778
182507
S1166
N
T
A
T
T
S
S
S
N
M
G
G
D
Q
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9V4C8
1500
160166
T606
A
V
S
I
A
T
S
T
S
D
P
L
S
V
R
Honey Bee
Apis mellifera
XP_624189
1550
166762
Q818
S
G
K
P
V
T
L
Q
M
S
G
G
I
G
A
Nematode Worm
Caenorhab. elegans
NP_501279
782
87341
K517
S
S
T
C
E
Q
K
K
T
D
E
S
G
L
E
Sea Urchin
Strong. purpuratus
XP_791039
1216
126587
V827
Q
T
T
L
I
S
T
V
G
T
T
P
T
V
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.3
99.4
94.8
N.A.
25.9
82
N.A.
72.5
73.7
25.3
28.7
N.A.
29.5
29.2
39.6
32
Protein Similarity:
100
99.8
99.6
97
N.A.
32
86.2
N.A.
80.8
83.9
31.5
36.3
N.A.
40.2
39.6
56
44.3
P-Site Identity:
100
100
100
93.3
N.A.
20
0
N.A.
0
20
20
20
N.A.
6.6
13.3
13.3
20
P-Site Similarity:
100
100
100
93.3
N.A.
33.3
13.3
N.A.
6.6
26.6
53.3
40
N.A.
33.3
13.3
26.6
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
8
0
15
0
0
8
8
8
0
8
8
0
58
% A
% Cys:
0
0
0
22
0
0
0
0
0
0
0
0
0
8
0
% C
% Asp:
8
0
8
8
0
0
0
0
0
15
29
0
8
0
0
% D
% Glu:
0
8
0
0
8
0
0
8
29
8
15
29
8
0
15
% E
% Phe:
0
0
8
29
0
0
0
0
0
0
0
0
0
0
8
% F
% Gly:
0
8
8
0
0
0
0
8
8
0
22
15
8
8
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
8
8
8
8
0
0
0
8
8
0
8
0
0
% I
% Lys:
0
0
8
0
0
8
36
8
0
15
8
0
0
0
8
% K
% Leu:
29
0
0
8
0
8
8
8
0
0
0
8
0
15
0
% L
% Met:
0
0
0
0
0
0
0
0
8
8
0
0
0
0
0
% M
% Asn:
15
8
0
8
0
0
0
0
15
0
0
0
0
0
0
% N
% Pro:
0
0
0
8
8
0
15
0
0
0
15
8
8
0
0
% P
% Gln:
8
0
0
0
0
8
0
8
8
0
0
0
0
15
0
% Q
% Arg:
0
0
0
0
0
0
8
0
0
0
0
0
8
0
8
% R
% Ser:
22
8
15
0
36
29
29
43
15
8
0
15
8
8
8
% S
% Thr:
15
65
43
15
22
43
8
8
15
8
8
15
43
0
0
% T
% Val:
0
8
0
0
8
0
0
8
0
29
0
8
0
22
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
29
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _