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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HCFC2
All Species:
22.12
Human Site:
S682
Identified Species:
37.44
UniProt:
Q9Y5Z7
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9Y5Z7
NP_037452.1
792
86779
S682
P
G
F
P
G
A
P
S
A
V
R
I
S
K
N
Chimpanzee
Pan troglodytes
XP_509326
792
86791
S682
P
G
F
P
G
A
P
S
A
V
R
I
S
K
N
Rhesus Macaque
Macaca mulatta
XP_001097074
792
86781
S682
P
G
F
P
G
A
P
S
A
V
R
I
S
K
N
Dog
Lupus familis
XP_532674
790
86251
S680
P
G
F
P
G
A
P
S
A
V
R
I
S
K
N
Cat
Felis silvestris
Mouse
Mus musculus
Q61191
2045
210519
C1905
P
G
F
P
G
A
P
C
A
I
K
I
S
K
S
Rat
Rattus norvegicus
Q5RKG2
723
79130
V621
T
V
R
I
S
K
N
V
E
G
I
H
L
S
W
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507728
758
83389
P652
S
W
E
P
P
V
S
P
S
G
N
I
L
E
Y
Chicken
Gallus gallus
XP_001234928
787
86020
S678
P
G
F
P
G
A
P
S
T
V
K
I
T
K
S
Frog
Xenopus laevis
NP_001087989
2101
219049
I1966
G
A
P
C
A
I
K
I
S
K
S
P
D
G
A
Zebra Danio
Brachydanio rerio
NP_001038529
1778
182507
I1643
G
A
P
C
A
I
K
I
S
K
S
P
D
G
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9V4C8
1500
160166
I1352
G
A
P
S
A
I
K
I
S
K
D
V
K
E
G
Honey Bee
Apis mellifera
XP_624189
1550
166762
S1396
P
G
F
P
G
A
P
S
A
I
K
I
S
K
T
Nematode Worm
Caenorhab. elegans
NP_501279
782
87341
I647
Y
P
S
A
P
S
S
I
R
I
T
K
S
H
E
Sea Urchin
Strong. purpuratus
XP_791039
1216
126587
A1106
G
P
W
S
E
I
S
A
F
K
T
C
L
P
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.3
99.4
94.8
N.A.
25.9
82
N.A.
72.5
73.7
25.3
28.7
N.A.
29.5
29.2
39.6
32
Protein Similarity:
100
99.8
99.6
97
N.A.
32
86.2
N.A.
80.8
83.9
31.5
36.3
N.A.
40.2
39.6
56
44.3
P-Site Identity:
100
100
100
100
N.A.
73.3
0
N.A.
13.3
73.3
0
0
N.A.
0
80
6.6
0
P-Site Similarity:
100
100
100
100
N.A.
93.3
0
N.A.
26.6
93.3
6.6
6.6
N.A.
20
93.3
20
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
22
0
8
22
50
0
8
43
0
0
0
0
0
15
% A
% Cys:
0
0
0
15
0
0
0
8
0
0
0
8
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
8
0
15
0
0
% D
% Glu:
0
0
8
0
8
0
0
0
8
0
0
0
0
15
8
% E
% Phe:
0
0
50
0
0
0
0
0
8
0
0
0
0
0
0
% F
% Gly:
29
50
0
0
50
0
0
0
0
15
0
0
0
15
15
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
8
0
8
0
% H
% Ile:
0
0
0
8
0
29
0
29
0
22
8
58
0
0
0
% I
% Lys:
0
0
0
0
0
8
22
0
0
29
22
8
8
50
0
% K
% Leu:
0
0
0
0
0
0
0
0
0
0
0
0
22
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
8
0
0
0
8
0
0
0
29
% N
% Pro:
50
15
22
58
15
0
50
8
0
0
0
15
0
8
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
8
0
0
0
0
0
8
0
29
0
0
0
0
% R
% Ser:
8
0
8
15
8
8
22
43
29
0
15
0
50
8
15
% S
% Thr:
8
0
0
0
0
0
0
0
8
0
15
0
8
0
8
% T
% Val:
0
8
0
0
0
8
0
8
0
36
0
8
0
0
0
% V
% Trp:
0
8
8
0
0
0
0
0
0
0
0
0
0
0
8
% W
% Tyr:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _