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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HCFC2
All Species:
26.06
Human Site:
S687
Identified Species:
44.1
UniProt:
Q9Y5Z7
Number Species:
13
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9Y5Z7
NP_037452.1
792
86779
S687
A
P
S
A
V
R
I
S
K
N
V
E
G
I
H
Chimpanzee
Pan troglodytes
XP_509326
792
86791
S687
A
P
S
A
V
R
I
S
K
N
V
E
G
I
H
Rhesus Macaque
Macaca mulatta
XP_001097074
792
86781
S687
A
P
S
A
V
R
I
S
K
N
V
E
G
I
H
Dog
Lupus familis
XP_532674
790
86251
S685
A
P
S
A
V
R
I
S
K
N
V
E
G
I
H
Cat
Felis silvestris
Mouse
Mus musculus
Q61191
2045
210519
S1910
A
P
C
A
I
K
I
S
K
S
P
D
G
A
H
Rat
Rattus norvegicus
Q5RKG2
723
79130
L626
K
N
V
E
G
I
H
L
S
W
E
P
P
T
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507728
758
83389
L657
V
S
P
S
G
N
I
L
E
Y
S
A
Y
L
A
Chicken
Gallus gallus
XP_001234928
787
86020
T683
A
P
S
T
V
K
I
T
K
S
V
D
C
I
H
Frog
Xenopus laevis
NP_001087989
2101
219049
D1971
I
K
I
S
K
S
P
D
G
A
H
L
T
W
E
Zebra Danio
Brachydanio rerio
NP_001038529
1778
182507
D1648
I
K
I
S
K
S
P
D
G
A
H
L
T
W
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9V4C8
1500
160166
K1357
I
K
I
S
K
D
V
K
E
G
A
H
L
T
W
Honey Bee
Apis mellifera
XP_624189
1550
166762
S1401
A
P
S
A
I
K
I
S
K
T
A
D
G
A
H
Nematode Worm
Caenorhab. elegans
NP_501279
782
87341
S652
S
S
I
R
I
T
K
S
H
E
G
A
Q
L
T
Sea Urchin
Strong. purpuratus
XP_791039
1216
126587
L1111
I
S
A
F
K
T
C
L
P
G
F
P
G
A
P
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.3
99.4
94.8
N.A.
25.9
82
N.A.
72.5
73.7
25.3
28.7
N.A.
29.5
29.2
39.6
32
Protein Similarity:
100
99.8
99.6
97
N.A.
32
86.2
N.A.
80.8
83.9
31.5
36.3
N.A.
40.2
39.6
56
44.3
P-Site Identity:
100
100
100
100
N.A.
53.3
0
N.A.
6.6
60
0
0
N.A.
0
60
6.6
6.6
P-Site Similarity:
100
100
100
100
N.A.
80
0
N.A.
26.6
86.6
6.6
6.6
N.A.
20
80
26.6
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
50
0
8
43
0
0
0
0
0
15
15
15
0
22
8
% A
% Cys:
0
0
8
0
0
0
8
0
0
0
0
0
8
0
0
% C
% Asp:
0
0
0
0
0
8
0
15
0
0
0
22
0
0
0
% D
% Glu:
0
0
0
8
0
0
0
0
15
8
8
29
0
0
15
% E
% Phe:
0
0
0
8
0
0
0
0
0
0
8
0
0
0
0
% F
% Gly:
0
0
0
0
15
0
0
0
15
15
8
0
50
0
0
% G
% His:
0
0
0
0
0
0
8
0
8
0
15
8
0
0
50
% H
% Ile:
29
0
29
0
22
8
58
0
0
0
0
0
0
36
0
% I
% Lys:
8
22
0
0
29
22
8
8
50
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
0
0
0
22
0
0
0
15
8
15
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
8
0
0
0
8
0
0
0
29
0
0
0
0
0
% N
% Pro:
0
50
8
0
0
0
15
0
8
0
8
15
8
0
8
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% Q
% Arg:
0
0
0
8
0
29
0
0
0
0
0
0
0
0
0
% R
% Ser:
8
22
43
29
0
15
0
50
8
15
8
0
0
0
8
% S
% Thr:
0
0
0
8
0
15
0
8
0
8
0
0
15
15
8
% T
% Val:
8
0
8
0
36
0
8
0
0
0
36
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
8
0
0
0
15
8
% W
% Tyr:
0
0
0
0
0
0
0
0
0
8
0
0
8
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _