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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: HCFC2 All Species: 45.45
Human Site: S97 Identified Species: 76.92
UniProt: Q9Y5Z7 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9Y5Z7 NP_037452.1 792 86779 S97 M V E Y G R Y S N E L Y E L Q
Chimpanzee Pan troglodytes XP_509326 792 86791 S97 M V E Y G R Y S N E L Y E L Q
Rhesus Macaque Macaca mulatta XP_001097074 792 86781 S97 M V E Y G R Y S N E L Y E L Q
Dog Lupus familis XP_532674 790 86251 S97 M V E Y G R Y S N E L Y E L Q
Cat Felis silvestris
Mouse Mus musculus Q61191 2045 210519 S107 M V E Y G K Y S N D L Y E L Q
Rat Rattus norvegicus Q5RKG2 723 79130 D47 G G N E G I A D E L H V Y N T
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001507728 758 83389 K65 R W L W K K V K P Q P P S S G
Chicken Gallus gallus XP_001234928 787 86020 S98 M V E Y G R Y S N D L Y E L Q
Frog Xenopus laevis NP_001087989 2101 219049 S105 M V E Y G K Y S N D L Y E L Q
Zebra Danio Brachydanio rerio NP_001038529 1778 182507 S106 M V E Y G K Y S N D L Y E L Q
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9V4C8 1500 160166 S148 M I E Y G K Y S N E L Y E L Q
Honey Bee Apis mellifera XP_624189 1550 166762 S96 M V E Y G K Y S D E L Y E L Q
Nematode Worm Caenorhab. elegans NP_501279 782 87341 I67 G G G N E G M I D E L H A Y N
Sea Urchin Strong. purpuratus XP_791039 1216 126587 S96 M V E Y G K Y S N E L Y E L Q
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.3 99.4 94.8 N.A. 25.9 82 N.A. 72.5 73.7 25.3 28.7 N.A. 29.5 29.2 39.6 32
Protein Similarity: 100 99.8 99.6 97 N.A. 32 86.2 N.A. 80.8 83.9 31.5 36.3 N.A. 40.2 39.6 56 44.3
P-Site Identity: 100 100 100 100 N.A. 86.6 6.6 N.A. 0 93.3 86.6 86.6 N.A. 86.6 86.6 13.3 93.3
P-Site Similarity: 100 100 100 100 N.A. 100 6.6 N.A. 20 100 100 100 N.A. 100 100 26.6 100
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 8 0 0 0 0 0 8 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 8 15 29 0 0 0 0 0 % D
% Glu: 0 0 79 8 8 0 0 0 8 58 0 0 79 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 15 15 8 0 86 8 0 0 0 0 0 0 0 0 8 % G
% His: 0 0 0 0 0 0 0 0 0 0 8 8 0 0 0 % H
% Ile: 0 8 0 0 0 8 0 8 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 8 50 0 8 0 0 0 0 0 0 0 % K
% Leu: 0 0 8 0 0 0 0 0 0 8 86 0 0 79 0 % L
% Met: 79 0 0 0 0 0 8 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 8 8 0 0 0 0 72 0 0 0 0 8 8 % N
% Pro: 0 0 0 0 0 0 0 0 8 0 8 8 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 8 0 0 0 0 79 % Q
% Arg: 8 0 0 0 0 36 0 0 0 0 0 0 0 0 0 % R
% Ser: 0 0 0 0 0 0 0 79 0 0 0 0 8 8 0 % S
% Thr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8 % T
% Val: 0 72 0 0 0 0 8 0 0 0 0 8 0 0 0 % V
% Trp: 0 8 0 8 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 79 0 0 79 0 0 0 0 79 8 8 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _