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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HCFC2
All Species:
13.64
Human Site:
T229
Identified Species:
23.08
UniProt:
Q9Y5Z7
Number Species:
13
Phosphosite Substitution
Charge Score:
0.38
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9Y5Z7
NP_037452.1
792
86779
T229
L
W
Q
L
D
L
E
T
M
S
W
S
K
P
E
Chimpanzee
Pan troglodytes
XP_509326
792
86791
T229
L
W
Q
L
D
L
E
T
M
S
W
S
K
P
E
Rhesus Macaque
Macaca mulatta
XP_001097074
792
86781
T229
L
W
Q
L
D
L
E
T
M
S
W
S
K
P
E
Dog
Lupus familis
XP_532674
790
86251
T229
L
W
Q
L
D
L
E
T
M
S
W
S
K
P
E
Cat
Felis silvestris
Mouse
Mus musculus
Q61191
2045
210519
D236
L
G
D
L
W
T
L
D
I
E
T
L
T
W
N
Rat
Rattus norvegicus
Q5RKG2
723
79130
V174
E
L
Q
H
G
S
G
V
V
G
W
S
V
P
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507728
758
83389
V203
R
S
L
H
T
A
N
V
I
G
N
K
M
Y
I
Chicken
Gallus gallus
XP_001234928
787
86020
E229
D
L
W
E
L
D
I
E
T
M
T
W
S
R
P
Frog
Xenopus laevis
NP_001087989
2101
219049
D234
L
G
D
L
W
I
L
D
I
D
T
L
T
W
S
Zebra Danio
Brachydanio rerio
NP_001038529
1778
182507
D235
L
G
D
L
W
T
L
D
I
D
T
L
T
W
N
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9V4C8
1500
160166
L277
R
L
G
D
L
W
L
L
E
T
D
S
M
T
W
Honey Bee
Apis mellifera
XP_624189
1550
166762
D224
L
G
D
L
W
Y
L
D
V
D
S
M
T
W
H
Nematode Worm
Caenorhab. elegans
NP_501279
782
87341
P194
Y
V
I
N
L
S
G
P
Q
H
L
I
W
E
K
Sea Urchin
Strong. purpuratus
XP_791039
1216
126587
N225
L
G
D
L
W
Q
L
N
M
D
T
H
T
W
I
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.3
99.4
94.8
N.A.
25.9
82
N.A.
72.5
73.7
25.3
28.7
N.A.
29.5
29.2
39.6
32
Protein Similarity:
100
99.8
99.6
97
N.A.
32
86.2
N.A.
80.8
83.9
31.5
36.3
N.A.
40.2
39.6
56
44.3
P-Site Identity:
100
100
100
100
N.A.
13.3
26.6
N.A.
0
0
13.3
13.3
N.A.
6.6
13.3
0
20
P-Site Similarity:
100
100
100
100
N.A.
20
33.3
N.A.
6.6
0
26.6
20
N.A.
13.3
20
6.6
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
8
0
36
8
29
8
0
29
0
29
8
0
0
0
0
% D
% Glu:
8
0
0
8
0
0
29
8
8
8
0
0
0
8
29
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
36
8
0
8
0
15
0
0
15
0
0
0
0
0
% G
% His:
0
0
0
15
0
0
0
0
0
8
0
8
0
0
8
% H
% Ile:
0
0
8
0
0
8
8
0
29
0
0
8
0
0
15
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
8
29
0
8
% K
% Leu:
65
22
8
65
22
29
43
8
0
0
8
22
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
36
8
0
8
15
0
0
% M
% Asn:
0
0
0
8
0
0
8
8
0
0
8
0
0
0
15
% N
% Pro:
0
0
0
0
0
0
0
8
0
0
0
0
0
36
8
% P
% Gln:
0
0
36
0
0
8
0
0
8
0
0
0
0
0
0
% Q
% Arg:
15
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% R
% Ser:
0
8
0
0
0
15
0
0
0
29
8
43
8
0
8
% S
% Thr:
0
0
0
0
8
15
0
29
8
8
36
0
36
8
0
% T
% Val:
0
8
0
0
0
0
0
15
15
0
0
0
8
0
0
% V
% Trp:
0
29
8
0
36
8
0
0
0
0
36
8
8
36
8
% W
% Tyr:
8
0
0
0
0
8
0
0
0
0
0
0
0
8
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _