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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HCFC2
All Species:
19.7
Human Site:
T438
Identified Species:
33.33
UniProt:
Q9Y5Z7
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9Y5Z7
NP_037452.1
792
86779
T438
D
T
I
N
S
T
K
T
E
Q
P
A
T
K
E
Chimpanzee
Pan troglodytes
XP_509326
792
86791
T438
D
T
I
N
S
T
K
T
E
Q
P
A
T
K
E
Rhesus Macaque
Macaca mulatta
XP_001097074
792
86781
T438
D
T
I
N
S
T
K
T
E
Q
P
A
T
K
E
Dog
Lupus familis
XP_532674
790
86251
T436
V
S
D
N
S
A
K
T
E
H
T
A
L
K
G
Cat
Felis silvestris
Mouse
Mus musculus
Q61191
2045
210519
S1451
T
V
T
S
N
M
S
S
N
Q
D
P
P
P
A
Rat
Rattus norvegicus
Q5RKG2
723
79130
P381
H
V
K
W
D
E
V
P
T
V
E
G
Y
L
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507728
758
83389
N411
P
K
G
I
V
E
S
N
A
T
V
H
S
S
F
Chicken
Gallus gallus
XP_001234928
787
86020
T436
D
N
V
S
E
T
V
T
V
A
A
P
E
N
K
Frog
Xenopus laevis
NP_001087989
2101
219049
T1249
T
N
I
T
S
T
T
T
D
V
T
A
N
V
G
Zebra Danio
Brachydanio rerio
NP_001038529
1778
182507
T1050
P
P
C
E
T
H
E
T
G
T
T
S
T
T
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9V4C8
1500
160166
T490
L
G
V
E
A
T
S
T
V
L
K
L
E
K
E
Honey Bee
Apis mellifera
XP_624189
1550
166762
N702
I
V
V
T
T
G
S
N
L
R
T
I
Q
A
V
Nematode Worm
Caenorhab. elegans
NP_501279
782
87341
I401
S
L
E
I
S
W
P
I
V
Q
G
A
S
G
Y
Sea Urchin
Strong. purpuratus
XP_791039
1216
126587
Q711
S
S
P
G
A
S
G
Q
V
S
G
N
T
I
Q
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.3
99.4
94.8
N.A.
25.9
82
N.A.
72.5
73.7
25.3
28.7
N.A.
29.5
29.2
39.6
32
Protein Similarity:
100
99.8
99.6
97
N.A.
32
86.2
N.A.
80.8
83.9
31.5
36.3
N.A.
40.2
39.6
56
44.3
P-Site Identity:
100
100
100
46.6
N.A.
6.6
0
N.A.
0
20
33.3
13.3
N.A.
26.6
0
20
6.6
P-Site Similarity:
100
100
100
53.3
N.A.
26.6
0
N.A.
6.6
40
40
33.3
N.A.
40
20
26.6
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
15
8
0
0
8
8
8
43
0
8
8
% A
% Cys:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
29
0
8
0
8
0
0
0
8
0
8
0
0
0
0
% D
% Glu:
0
0
8
15
8
15
8
0
29
0
8
0
15
0
29
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% F
% Gly:
0
8
8
8
0
8
8
0
8
0
15
8
0
8
15
% G
% His:
8
0
0
0
0
8
0
0
0
8
0
8
0
0
0
% H
% Ile:
8
0
29
15
0
0
0
8
0
0
0
8
0
8
0
% I
% Lys:
0
8
8
0
0
0
29
0
0
0
8
0
0
36
8
% K
% Leu:
8
8
0
0
0
0
0
0
8
8
0
8
8
8
8
% L
% Met:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
15
0
29
8
0
0
15
8
0
0
8
8
8
0
% N
% Pro:
15
8
8
0
0
0
8
8
0
0
22
15
8
8
0
% P
% Gln:
0
0
0
0
0
0
0
8
0
36
0
0
8
0
8
% Q
% Arg:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% R
% Ser:
15
15
0
15
43
8
29
8
0
8
0
8
15
8
0
% S
% Thr:
15
22
8
15
15
43
8
58
8
15
29
0
36
8
8
% T
% Val:
8
22
22
0
8
0
15
0
29
15
8
0
0
8
8
% V
% Trp:
0
0
0
8
0
8
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _