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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HCFC2
All Species:
10.61
Human Site:
T458
Identified Species:
17.95
UniProt:
Q9Y5Z7
Number Species:
13
Phosphosite Substitution
Charge Score:
0.15
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9Y5Z7
NP_037452.1
792
86779
T458
K
P
D
F
K
A
L
T
D
S
N
A
I
L
Y
Chimpanzee
Pan troglodytes
XP_509326
792
86791
M458
K
P
E
F
K
A
L
M
D
S
N
A
I
L
Y
Rhesus Macaque
Macaca mulatta
XP_001097074
792
86781
T458
K
P
D
F
K
A
L
T
D
S
N
A
I
L
Y
Dog
Lupus familis
XP_532674
790
86251
S456
R
P
D
L
K
A
S
S
D
S
N
A
T
L
H
Cat
Felis silvestris
Mouse
Mus musculus
Q61191
2045
210519
D1471
E
V
A
S
T
Q
G
D
S
T
N
I
T
S
A
Rat
Rattus norvegicus
Q5RKG2
723
79130
P401
L
T
H
Q
A
A
S
P
D
A
S
A
A
P
N
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507728
758
83389
A431
A
A
N
N
D
G
F
A
V
E
M
L
K
R
N
Chicken
Gallus gallus
XP_001234928
787
86020
T456
M
K
N
H
A
D
A
T
G
F
K
E
S
N
A
Frog
Xenopus laevis
NP_001087989
2101
219049
D1269
N
V
V
N
V
C
S
D
P
R
S
E
T
Y
E
Zebra Danio
Brachydanio rerio
NP_001038529
1778
182507
T1070
M
G
T
A
P
A
G
T
V
Q
R
V
C
S
N
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9V4C8
1500
160166
V510
G
C
Q
P
E
T
N
V
Q
P
S
V
N
D
L
Honey Bee
Apis mellifera
XP_624189
1550
166762
I722
G
G
G
Q
T
G
N
I
T
T
P
V
N
V
L
Nematode Worm
Caenorhab. elegans
NP_501279
782
87341
S421
F
G
D
A
K
E
Q
S
V
S
P
I
K
R
A
Sea Urchin
Strong. purpuratus
XP_791039
1216
126587
Q731
G
A
K
S
T
L
N
Q
A
S
A
A
N
L
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.3
99.4
94.8
N.A.
25.9
82
N.A.
72.5
73.7
25.3
28.7
N.A.
29.5
29.2
39.6
32
Protein Similarity:
100
99.8
99.6
97
N.A.
32
86.2
N.A.
80.8
83.9
31.5
36.3
N.A.
40.2
39.6
56
44.3
P-Site Identity:
100
86.6
100
60
N.A.
6.6
20
N.A.
0
6.6
0
13.3
N.A.
0
0
20
20
P-Site Similarity:
100
93.3
100
80
N.A.
20
33.3
N.A.
6.6
13.3
6.6
13.3
N.A.
13.3
13.3
26.6
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
15
8
15
15
43
8
8
8
8
8
43
8
0
22
% A
% Cys:
0
8
0
0
0
8
0
0
0
0
0
0
8
0
0
% C
% Asp:
0
0
29
0
8
8
0
15
36
0
0
0
0
8
0
% D
% Glu:
8
0
8
0
8
8
0
0
0
8
0
15
0
0
8
% E
% Phe:
8
0
0
22
0
0
8
0
0
8
0
0
0
0
0
% F
% Gly:
22
22
8
0
0
15
15
0
8
0
0
0
0
0
0
% G
% His:
0
0
8
8
0
0
0
0
0
0
0
0
0
0
8
% H
% Ile:
0
0
0
0
0
0
0
8
0
0
0
15
22
0
0
% I
% Lys:
22
8
8
0
36
0
0
0
0
0
8
0
15
0
0
% K
% Leu:
8
0
0
8
0
8
22
0
0
0
0
8
0
36
22
% L
% Met:
15
0
0
0
0
0
0
8
0
0
8
0
0
0
0
% M
% Asn:
8
0
15
15
0
0
22
0
0
0
36
0
22
8
22
% N
% Pro:
0
29
0
8
8
0
0
8
8
8
15
0
0
8
0
% P
% Gln:
0
0
8
15
0
8
8
8
8
8
0
0
0
0
0
% Q
% Arg:
8
0
0
0
0
0
0
0
0
8
8
0
0
15
0
% R
% Ser:
0
0
0
15
0
0
22
15
8
43
22
0
8
15
0
% S
% Thr:
0
8
8
0
22
8
0
29
8
15
0
0
22
0
0
% T
% Val:
0
15
8
0
8
0
0
8
22
0
0
22
0
8
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
22
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _