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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HCFC2
All Species:
10.91
Human Site:
T577
Identified Species:
18.46
UniProt:
Q9Y5Z7
Number Species:
13
Phosphosite Substitution
Charge Score:
0.23
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9Y5Z7
NP_037452.1
792
86779
T577
V
E
T
H
A
T
A
T
P
F
S
K
E
T
P
Chimpanzee
Pan troglodytes
XP_509326
792
86791
T577
V
E
T
H
A
T
A
T
P
F
S
K
E
T
P
Rhesus Macaque
Macaca mulatta
XP_001097074
792
86781
M577
V
E
T
H
A
T
A
M
P
F
S
K
E
T
P
Dog
Lupus familis
XP_532674
790
86251
M575
V
E
A
H
A
T
A
M
P
F
S
K
E
T
P
Cat
Felis silvestris
Mouse
Mus musculus
Q61191
2045
210519
E1590
P
P
P
P
T
Q
S
E
V
D
Q
L
S
L
P
Rat
Rattus norvegicus
Q5RKG2
723
79130
P520
S
K
E
T
P
S
N
P
V
A
I
L
K
A
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507728
758
83389
G550
D
R
R
W
C
D
V
G
I
F
K
N
N
T
A
Chicken
Gallus gallus
XP_001234928
787
86020
S575
G
Q
A
N
D
S
H
S
S
R
T
S
Q
R
Q
Frog
Xenopus laevis
NP_001087989
2101
219049
A1388
N
T
D
Q
V
I
S
A
G
S
T
K
T
E
P
Zebra Danio
Brachydanio rerio
NP_001038529
1778
182507
E984
N
P
P
C
E
T
H
E
T
G
T
T
N
T
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9V4C8
1500
160166
S629
V
V
L
S
S
S
S
S
T
L
R
I
V
P
S
Honey Bee
Apis mellifera
XP_624189
1550
166762
S841
S
S
T
I
V
T
T
S
S
A
S
E
T
I
D
Nematode Worm
Caenorhab. elegans
NP_501279
782
87341
D540
P
S
D
A
G
E
T
D
E
M
K
E
E
N
G
Sea Urchin
Strong. purpuratus
XP_791039
1216
126587
T850
V
A
E
D
A
S
E
T
K
P
T
A
T
E
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.3
99.4
94.8
N.A.
25.9
82
N.A.
72.5
73.7
25.3
28.7
N.A.
29.5
29.2
39.6
32
Protein Similarity:
100
99.8
99.6
97
N.A.
32
86.2
N.A.
80.8
83.9
31.5
36.3
N.A.
40.2
39.6
56
44.3
P-Site Identity:
100
100
93.3
86.6
N.A.
6.6
0
N.A.
13.3
0
13.3
13.3
N.A.
6.6
20
6.6
20
P-Site Similarity:
100
100
93.3
86.6
N.A.
13.3
20
N.A.
13.3
40
26.6
20
N.A.
33.3
33.3
13.3
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
15
8
36
0
29
8
0
15
0
8
0
8
15
% A
% Cys:
0
0
0
8
8
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
8
0
15
8
8
8
0
8
0
8
0
0
0
0
8
% D
% Glu:
0
29
15
0
8
8
8
15
8
0
0
15
36
15
15
% E
% Phe:
0
0
0
0
0
0
0
0
0
36
0
0
0
0
0
% F
% Gly:
8
0
0
0
8
0
0
8
8
8
0
0
0
0
8
% G
% His:
0
0
0
29
0
0
15
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
8
0
8
0
0
8
0
8
8
0
8
0
% I
% Lys:
0
8
0
0
0
0
0
0
8
0
15
36
8
0
0
% K
% Leu:
0
0
8
0
0
0
0
0
0
8
0
15
0
8
0
% L
% Met:
0
0
0
0
0
0
0
15
0
8
0
0
0
0
0
% M
% Asn:
15
0
0
8
0
0
8
0
0
0
0
8
15
8
0
% N
% Pro:
15
15
15
8
8
0
0
8
29
8
0
0
0
8
43
% P
% Gln:
0
8
0
8
0
8
0
0
0
0
8
0
8
0
8
% Q
% Arg:
0
8
8
0
0
0
0
0
0
8
8
0
0
8
0
% R
% Ser:
15
15
0
8
8
29
22
22
15
8
36
8
8
0
8
% S
% Thr:
0
8
29
8
8
43
15
22
15
0
29
8
22
43
0
% T
% Val:
43
8
0
0
15
0
8
0
15
0
0
0
8
0
0
% V
% Trp:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _