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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HCFC2
All Species:
38.18
Human Site:
Y159
Identified Species:
64.62
UniProt:
Q9Y5Z7
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9Y5Z7
NP_037452.1
792
86779
Y159
S
N
N
N
V
P
R
Y
L
N
D
F
Y
E
L
Chimpanzee
Pan troglodytes
XP_509326
792
86791
Y159
S
N
N
N
V
P
R
Y
L
N
D
F
Y
E
L
Rhesus Macaque
Macaca mulatta
XP_001097074
792
86781
Y159
S
N
N
N
V
P
R
Y
L
N
D
F
Y
E
L
Dog
Lupus familis
XP_532674
790
86251
Y159
S
N
N
N
V
P
R
Y
L
N
D
F
Y
E
L
Cat
Felis silvestris
Mouse
Mus musculus
Q61191
2045
210519
Y169
P
K
N
N
I
P
R
Y
L
N
D
L
Y
I
L
Rat
Rattus norvegicus
Q5RKG2
723
79130
L109
E
L
Q
A
S
R
W
L
W
K
K
V
K
P
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507728
758
83389
G127
Q
H
G
S
G
V
V
G
W
S
I
P
V
T
K
Chicken
Gallus gallus
XP_001234928
787
86020
Y160
S
N
N
N
V
P
R
Y
L
N
D
F
Y
E
L
Frog
Xenopus laevis
NP_001087989
2101
219049
Y167
P
K
N
N
I
P
R
Y
L
N
D
L
Y
I
L
Zebra Danio
Brachydanio rerio
NP_001038529
1778
182507
Y168
P
K
N
N
I
P
R
Y
L
N
D
L
Y
T
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9V4C8
1500
160166
Y210
P
K
N
N
I
P
K
Y
L
N
D
L
Y
I
L
Honey Bee
Apis mellifera
XP_624189
1550
166762
Y158
H
K
N
N
I
P
R
Y
L
N
D
L
Y
T
L
Nematode Worm
Caenorhab. elegans
NP_501279
782
87341
W129
Y
E
L
Q
S
T
R
W
E
W
R
R
L
N
P
Sea Urchin
Strong. purpuratus
XP_791039
1216
126587
Y158
P
K
N
N
I
P
R
Y
L
N
D
L
Y
S
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.3
99.4
94.8
N.A.
25.9
82
N.A.
72.5
73.7
25.3
28.7
N.A.
29.5
29.2
39.6
32
Protein Similarity:
100
99.8
99.6
97
N.A.
32
86.2
N.A.
80.8
83.9
31.5
36.3
N.A.
40.2
39.6
56
44.3
P-Site Identity:
100
100
100
100
N.A.
66.6
0
N.A.
0
100
66.6
66.6
N.A.
60
66.6
6.6
66.6
P-Site Similarity:
100
100
100
100
N.A.
73.3
0
N.A.
20
100
73.3
73.3
N.A.
73.3
73.3
13.3
73.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
79
0
0
0
0
% D
% Glu:
8
8
0
0
0
0
0
0
8
0
0
0
0
36
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
36
0
0
0
% F
% Gly:
0
0
8
0
8
0
0
8
0
0
0
0
0
0
0
% G
% His:
8
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
43
0
0
0
0
0
8
0
0
22
0
% I
% Lys:
0
43
0
0
0
0
8
0
0
8
8
0
8
0
8
% K
% Leu:
0
8
8
0
0
0
0
8
79
0
0
43
8
0
79
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
36
79
79
0
0
0
0
0
79
0
0
0
8
0
% N
% Pro:
36
0
0
0
0
79
0
0
0
0
0
8
0
8
8
% P
% Gln:
8
0
8
8
0
0
0
0
0
0
0
0
0
0
8
% Q
% Arg:
0
0
0
0
0
8
79
0
0
0
8
8
0
0
0
% R
% Ser:
36
0
0
8
15
0
0
0
0
8
0
0
0
8
0
% S
% Thr:
0
0
0
0
0
8
0
0
0
0
0
0
0
22
0
% T
% Val:
0
0
0
0
36
8
8
0
0
0
0
8
8
0
0
% V
% Trp:
0
0
0
0
0
0
8
8
15
8
0
0
0
0
0
% W
% Tyr:
8
0
0
0
0
0
0
79
0
0
0
0
79
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _