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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HCFC2
All Species:
13.64
Human Site:
Y560
Identified Species:
23.08
UniProt:
Q9Y5Z7
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9Y5Z7
NP_037452.1
792
86779
Y560
K
S
E
V
D
E
T
Y
A
L
P
A
T
K
I
Chimpanzee
Pan troglodytes
XP_509326
792
86791
Y560
K
S
E
V
D
E
T
Y
A
L
P
A
T
K
I
Rhesus Macaque
Macaca mulatta
XP_001097074
792
86781
Y560
K
S
E
V
D
E
T
Y
A
L
P
A
T
K
I
Dog
Lupus familis
XP_532674
790
86251
C558
K
S
E
V
D
E
T
C
A
L
P
A
T
K
I
Cat
Felis silvestris
Mouse
Mus musculus
Q61191
2045
210519
S1573
S
G
Q
E
P
T
T
S
A
V
V
A
T
V
V
Rat
Rattus norvegicus
Q5RKG2
723
79130
V503
P
A
T
K
I
S
R
V
E
A
H
A
A
A
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507728
758
83389
L533
P
L
S
K
K
V
P
L
K
S
V
T
P
G
K
Chicken
Gallus gallus
XP_001234928
787
86020
Y558
S
E
A
A
E
T
A
Y
F
M
P
S
T
K
V
Frog
Xenopus laevis
NP_001087989
2101
219049
Q1371
R
S
N
I
G
A
E
Q
A
A
N
I
Q
Q
L
Zebra Danio
Brachydanio rerio
NP_001038529
1778
182507
Q1172
S
S
N
M
G
G
D
Q
A
G
A
V
Q
R
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9V4C8
1500
160166
V612
S
T
S
D
P
L
S
V
R
V
P
S
T
M
S
Honey Bee
Apis mellifera
XP_624189
1550
166762
G824
L
Q
M
S
G
G
I
G
A
K
T
V
T
L
M
Nematode Worm
Caenorhab. elegans
NP_501279
782
87341
L523
K
K
T
D
E
S
G
L
E
E
D
S
E
K
D
Sea Urchin
Strong. purpuratus
XP_791039
1216
126587
V833
T
V
G
T
T
P
T
V
S
L
P
S
T
D
Q
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.3
99.4
94.8
N.A.
25.9
82
N.A.
72.5
73.7
25.3
28.7
N.A.
29.5
29.2
39.6
32
Protein Similarity:
100
99.8
99.6
97
N.A.
32
86.2
N.A.
80.8
83.9
31.5
36.3
N.A.
40.2
39.6
56
44.3
P-Site Identity:
100
100
100
93.3
N.A.
26.6
6.6
N.A.
0
26.6
13.3
13.3
N.A.
13.3
13.3
13.3
26.6
P-Site Similarity:
100
100
100
93.3
N.A.
46.6
13.3
N.A.
0
53.3
40
33.3
N.A.
40
20
26.6
40
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
8
8
0
8
8
0
58
15
8
43
8
8
0
% A
% Cys:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
15
29
0
8
0
0
0
8
0
0
8
8
% D
% Glu:
0
8
29
8
15
29
8
0
15
8
0
0
8
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% F
% Gly:
0
8
8
0
22
15
8
8
0
8
0
0
0
8
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% H
% Ile:
0
0
0
8
8
0
8
0
0
0
0
8
0
0
29
% I
% Lys:
36
8
0
15
8
0
0
0
8
8
0
0
0
43
8
% K
% Leu:
8
8
0
0
0
8
0
15
0
36
0
0
0
8
8
% L
% Met:
0
0
8
8
0
0
0
0
0
8
0
0
0
8
8
% M
% Asn:
0
0
15
0
0
0
0
0
0
0
8
0
0
0
0
% N
% Pro:
15
0
0
0
15
8
8
0
0
0
50
0
8
0
0
% P
% Gln:
0
8
8
0
0
0
0
15
0
0
0
0
15
8
8
% Q
% Arg:
8
0
0
0
0
0
8
0
8
0
0
0
0
8
0
% R
% Ser:
29
43
15
8
0
15
8
8
8
8
0
29
0
0
8
% S
% Thr:
8
8
15
8
8
15
43
0
0
0
8
8
65
0
8
% T
% Val:
0
8
0
29
0
8
0
22
0
15
15
15
0
8
22
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
29
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _