KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HCFC2
All Species:
19.39
Human Site:
Y615
Identified Species:
32.82
UniProt:
Q9Y5Z7
Number Species:
13
Phosphosite Substitution
Charge Score:
0.15
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9Y5Z7
NP_037452.1
792
86779
Y615
T
A
L
V
S
Q
F
Y
L
L
P
K
G
K
Q
Chimpanzee
Pan troglodytes
XP_509326
792
86791
Y615
T
A
L
V
S
Q
F
Y
L
L
P
K
G
K
Q
Rhesus Macaque
Macaca mulatta
XP_001097074
792
86781
Y615
T
A
L
V
S
Q
F
Y
L
L
P
K
G
K
Q
Dog
Lupus familis
XP_532674
790
86251
Y613
T
A
L
V
S
Q
F
Y
L
L
P
K
G
K
Q
Cat
Felis silvestris
Mouse
Mus musculus
Q61191
2045
210519
Y1838
T
S
V
M
V
T
H
Y
F
L
P
P
D
D
A
Rat
Rattus norvegicus
Q5RKG2
723
79130
M555
L
P
K
G
K
Q
S
M
S
K
V
G
N
A
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507728
758
83389
S585
N
P
N
V
P
D
Y
S
L
L
K
K
Q
D
L
Chicken
Gallus gallus
XP_001234928
787
86020
L611
A
V
V
S
Q
F
Y
L
L
P
E
E
T
L
N
Frog
Xenopus laevis
NP_001087989
2101
219049
H1895
A
T
N
M
M
V
T
H
Y
Y
L
P
A
D
D
Zebra Danio
Brachydanio rerio
NP_001038529
1778
182507
F1572
T
N
T
V
V
T
H
F
Y
M
P
A
D
D
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9V4C8
1500
160166
D1281
H
T
V
T
S
Y
I
D
S
N
C
I
S
D
S
Honey Bee
Apis mellifera
XP_624189
1550
166762
H1329
E
S
R
F
T
V
Q
H
Y
Y
L
P
G
D
D
Nematode Worm
Caenorhab. elegans
NP_501279
782
87341
E578
N
D
R
Q
Q
S
L
E
K
Q
L
N
D
L
I
Sea Urchin
Strong. purpuratus
XP_791039
1216
126587
Y1035
K
K
D
V
N
Q
W
Y
D
V
G
I
I
K
T
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.3
99.4
94.8
N.A.
25.9
82
N.A.
72.5
73.7
25.3
28.7
N.A.
29.5
29.2
39.6
32
Protein Similarity:
100
99.8
99.6
97
N.A.
32
86.2
N.A.
80.8
83.9
31.5
36.3
N.A.
40.2
39.6
56
44.3
P-Site Identity:
100
100
100
100
N.A.
26.6
6.6
N.A.
26.6
6.6
0
20
N.A.
6.6
6.6
0
26.6
P-Site Similarity:
100
100
100
100
N.A.
46.6
6.6
N.A.
33.3
26.6
13.3
33.3
N.A.
13.3
26.6
0
46.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
15
29
0
0
0
0
0
0
0
0
0
8
8
8
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% C
% Asp:
0
8
8
0
0
8
0
8
8
0
0
0
22
43
22
% D
% Glu:
8
0
0
0
0
0
0
8
0
0
8
8
0
0
0
% E
% Phe:
0
0
0
8
0
8
29
8
8
0
0
0
0
0
0
% F
% Gly:
0
0
0
8
0
0
0
0
0
0
8
8
36
0
0
% G
% His:
8
0
0
0
0
0
15
15
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
8
0
0
0
0
15
8
0
8
% I
% Lys:
8
8
8
0
8
0
0
0
8
8
8
36
0
36
0
% K
% Leu:
8
0
29
0
0
0
8
8
43
43
22
0
0
15
8
% L
% Met:
0
0
0
15
8
0
0
8
0
8
0
0
0
0
0
% M
% Asn:
15
8
15
0
8
0
0
0
0
8
0
8
8
0
8
% N
% Pro:
0
15
0
0
8
0
0
0
0
8
43
22
0
0
0
% P
% Gln:
0
0
0
8
15
43
8
0
0
8
0
0
8
0
29
% Q
% Arg:
0
0
15
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
15
0
8
36
8
8
8
15
0
0
0
8
0
15
% S
% Thr:
43
15
8
8
8
15
8
0
0
0
0
0
8
0
8
% T
% Val:
0
8
22
50
15
15
0
0
0
8
8
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
8
15
43
22
15
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _