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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PUS1
All Species:
34.55
Human Site:
S225
Identified Species:
69.09
UniProt:
Q9Y606
Number Species:
11
Phosphosite Substitution
Charge Score:
0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9Y606
NP_001002019.1
427
47470
S225
Q
D
E
T
Y
R
L
S
A
E
T
L
Q
Q
V
Chimpanzee
Pan troglodytes
XP_001139560
427
47570
S225
Q
D
E
T
Y
R
L
S
A
E
T
L
Q
Q
V
Rhesus Macaque
Macaca mulatta
XP_001113470
483
53046
S281
Q
D
E
T
Y
R
L
S
A
E
T
L
Q
Q
V
Dog
Lupus familis
XP_852307
409
45618
S202
Q
D
E
S
Y
R
L
S
A
E
T
L
Q
R
V
Cat
Felis silvestris
Mouse
Mus musculus
Q9WU56
423
47484
S221
Q
D
E
S
Y
R
L
S
A
E
T
L
Q
Q
V
Rat
Rattus norvegicus
Q4KM92
423
47497
S221
Q
D
E
S
Y
R
L
S
A
E
T
L
Q
Q
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510884
469
53590
S241
Q
D
E
T
Y
R
L
S
P
E
V
L
E
R
V
Chicken
Gallus gallus
XP_415090
409
46045
S205
Q
E
E
A
H
R
L
S
R
E
T
L
E
K
V
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001008603
376
42830
H199
F
C
L
Y
K
G
T
H
N
F
H
N
F
T
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_650899
410
47206
S209
V
H
D
T
F
R
I
S
P
E
L
L
Q
K
V
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001202324
494
54942
D209
L
E
K
Y
R
V
S
D
E
K
I
E
E
V
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P53167
370
41857
S198
S
G
Y
C
L
S
P
S
K
L
D
A
F
E
A
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.8
83
74.9
N.A.
84.5
84.7
N.A.
65.6
71.4
N.A.
56.6
N.A.
40.5
N.A.
N.A.
45.3
Protein Similarity:
100
99
84
80
N.A.
89.6
90.4
N.A.
75.4
81.9
N.A.
71.1
N.A.
58.5
N.A.
N.A.
59.1
P-Site Identity:
100
100
100
86.6
N.A.
93.3
93.3
N.A.
73.3
60
N.A.
0
N.A.
46.6
N.A.
N.A.
0
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
86.6
86.6
N.A.
0
N.A.
73.3
N.A.
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
20.6
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
33.7
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
9
0
0
0
0
50
0
0
9
0
0
9
% A
% Cys:
0
9
0
9
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
59
9
0
0
0
0
9
0
0
9
0
0
0
0
% D
% Glu:
0
17
67
0
0
0
0
0
9
75
0
9
25
9
0
% E
% Phe:
9
0
0
0
9
0
0
0
0
9
0
0
17
0
0
% F
% Gly:
0
9
0
0
0
9
0
0
0
0
0
0
0
0
9
% G
% His:
0
9
0
0
9
0
0
9
0
0
9
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
9
0
0
0
9
0
0
0
0
% I
% Lys:
0
0
9
0
9
0
0
0
9
9
0
0
0
17
0
% K
% Leu:
9
0
9
0
9
0
67
0
0
9
9
75
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
9
0
0
9
0
0
0
% N
% Pro:
0
0
0
0
0
0
9
0
17
0
0
0
0
0
0
% P
% Gln:
67
0
0
0
0
0
0
0
0
0
0
0
59
42
0
% Q
% Arg:
0
0
0
0
9
75
0
0
9
0
0
0
0
17
0
% R
% Ser:
9
0
0
25
0
9
9
84
0
0
0
0
0
0
9
% S
% Thr:
0
0
0
42
0
0
9
0
0
0
59
0
0
9
0
% T
% Val:
9
0
0
0
0
9
0
0
0
0
9
0
0
9
75
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
9
17
59
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _