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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PUS1 All Species: 6.06
Human Site: S24 Identified Species: 12.12
UniProt: Q9Y606 Number Species: 11
    Phosphosite Substitution
    Charge Score: -0.18
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9Y606 NP_001002019.1 427 47470 S24 L R L G P R P S C S P R M A G
Chimpanzee Pan troglodytes XP_001139560 427 47570 S24 L R L G P R P S C S P R M A G
Rhesus Macaque Macaca mulatta XP_001113470 483 53046 G80 G K P T G R G G S S P R M A G
Dog Lupus familis XP_852307 409 45618 Q17 L V S A A L E Q D R K A R S G
Cat Felis silvestris
Mouse Mus musculus Q9WU56 423 47484 P26 A R P G P R V P G L P P M A G
Rat Rattus norvegicus Q4KM92 423 47497 P26 A R P G P R V P G L P P M A G
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001510884 469 53590 L39 L Q L Q R L F L H K P S M A E
Chicken Gallus gallus XP_415090 409 46045 R18 A S G G F R P R N V P L A M A
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_001008603 376 42830 P17 K R A A D D D P H T E T E H E
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_650899 410 47206 K16 E V E K E A R K E A K E L E G
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_001202324 494 54942 T19 S S D G D S L T V S P A T A D
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P53167 370 41857 N16 G Y Y G M Q Y N P P H K T I E
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.8 83 74.9 N.A. 84.5 84.7 N.A. 65.6 71.4 N.A. 56.6 N.A. 40.5 N.A. N.A. 45.3
Protein Similarity: 100 99 84 80 N.A. 89.6 90.4 N.A. 75.4 81.9 N.A. 71.1 N.A. 58.5 N.A. N.A. 59.1
P-Site Identity: 100 100 46.6 13.3 N.A. 53.3 53.3 N.A. 33.3 26.6 N.A. 6.6 N.A. 6.6 N.A. N.A. 26.6
P-Site Similarity: 100 100 53.3 20 N.A. 53.3 53.3 N.A. 40 26.6 N.A. 13.3 N.A. 20 N.A. N.A. 33.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. 20.6 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 33.7 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 6.6 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 26.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 25 0 9 17 9 9 0 0 0 9 0 17 9 59 9 % A
% Cys: 0 0 0 0 0 0 0 0 17 0 0 0 0 0 0 % C
% Asp: 0 0 9 0 17 9 9 0 9 0 0 0 0 0 9 % D
% Glu: 9 0 9 0 9 0 9 0 9 0 9 9 9 9 25 % E
% Phe: 0 0 0 0 9 0 9 0 0 0 0 0 0 0 0 % F
% Gly: 17 0 9 59 9 0 9 9 17 0 0 0 0 0 59 % G
% His: 0 0 0 0 0 0 0 0 17 0 9 0 0 9 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 9 0 % I
% Lys: 9 9 0 9 0 0 0 9 0 9 17 9 0 0 0 % K
% Leu: 34 0 25 0 0 17 9 9 0 17 0 9 9 0 0 % L
% Met: 0 0 0 0 9 0 0 0 0 0 0 0 50 9 0 % M
% Asn: 0 0 0 0 0 0 0 9 9 0 0 0 0 0 0 % N
% Pro: 0 0 25 0 34 0 25 25 9 9 67 17 0 0 0 % P
% Gln: 0 9 0 9 0 9 0 9 0 0 0 0 0 0 0 % Q
% Arg: 0 42 0 0 9 50 9 9 0 9 0 25 9 0 0 % R
% Ser: 9 17 9 0 0 9 0 17 9 34 0 9 0 9 0 % S
% Thr: 0 0 0 9 0 0 0 9 0 9 0 9 17 0 0 % T
% Val: 0 17 0 0 0 0 17 0 9 9 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 9 9 0 0 0 9 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _