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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PUS1 All Species: 32.12
Human Site: S258 Identified Species: 64.24
UniProt: Q9Y606 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0.09
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9Y606 NP_001002019.1 427 47470 S258 Q K G P Q D P S A C R Y I L E
Chimpanzee Pan troglodytes XP_001139560 427 47570 S258 Q K G P Q D P S A C R Y I L E
Rhesus Macaque Macaca mulatta XP_001113470 483 53046 S314 Q K G P Q E P S A R R Y I L E
Dog Lupus familis XP_852307 409 45618 S235 Q K G P Q E A S A R R Y I L D
Cat Felis silvestris
Mouse Mus musculus Q9WU56 423 47484 S254 Q K G P R E P S A R R Y I L E
Rat Rattus norvegicus Q4KM92 423 47497 S254 Q K G P R E P S A R R Y I L E
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001510884 469 53590 S274 Q K G P K D A S G M R Y I M E
Chicken Gallus gallus XP_415090 409 46045 S238 Q K G P K D P S A R R Y I M E
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_001008603 376 42830 D232 G E P F I R K D V E F A V I T
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_650899 410 47206 S242 K K S F L D P S S K R F I M S
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_001202324 494 54942 A242 K A F T D P S A N R Y I K E F
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P53167 370 41857 Q231 L W G D P S A Q R H I K K V V
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.8 83 74.9 N.A. 84.5 84.7 N.A. 65.6 71.4 N.A. 56.6 N.A. 40.5 N.A. N.A. 45.3
Protein Similarity: 100 99 84 80 N.A. 89.6 90.4 N.A. 75.4 81.9 N.A. 71.1 N.A. 58.5 N.A. N.A. 59.1
P-Site Identity: 100 100 86.6 73.3 N.A. 80 80 N.A. 66.6 80 N.A. 0 N.A. 40 N.A. N.A. 0
P-Site Similarity: 100 100 93.3 86.6 N.A. 93.3 93.3 N.A. 80 93.3 N.A. 20 N.A. 66.6 N.A. N.A. 13.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. 20.6 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 33.7 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 6.6 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 13.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 9 0 0 0 0 25 9 59 0 0 9 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 17 0 0 0 0 0 % C
% Asp: 0 0 0 9 9 42 0 9 0 0 0 0 0 0 9 % D
% Glu: 0 9 0 0 0 34 0 0 0 9 0 0 0 9 59 % E
% Phe: 0 0 9 17 0 0 0 0 0 0 9 9 0 0 9 % F
% Gly: 9 0 75 0 0 0 0 0 9 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 9 0 0 0 0 0 % H
% Ile: 0 0 0 0 9 0 0 0 0 0 9 9 75 9 0 % I
% Lys: 17 75 0 0 17 0 9 0 0 9 0 9 17 0 0 % K
% Leu: 9 0 0 0 9 0 0 0 0 0 0 0 0 50 0 % L
% Met: 0 0 0 0 0 0 0 0 0 9 0 0 0 25 0 % M
% Asn: 0 0 0 0 0 0 0 0 9 0 0 0 0 0 0 % N
% Pro: 0 0 9 67 9 9 59 0 0 0 0 0 0 0 0 % P
% Gln: 67 0 0 0 34 0 0 9 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 17 9 0 0 9 50 75 0 0 0 0 % R
% Ser: 0 0 9 0 0 9 9 75 9 0 0 0 0 0 9 % S
% Thr: 0 0 0 9 0 0 0 0 0 0 0 0 0 0 9 % T
% Val: 0 0 0 0 0 0 0 0 9 0 0 0 9 9 9 % V
% Trp: 0 9 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 9 67 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _