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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PUS1
All Species:
32.73
Human Site:
Y374
Identified Species:
65.45
UniProt:
Q9Y606
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9Y606
NP_001002019.1
427
47470
Y374
A
F
K
E
E
H
I
Y
P
T
I
I
G
T
E
Chimpanzee
Pan troglodytes
XP_001139560
427
47570
Y374
A
F
K
E
E
H
I
Y
P
T
I
I
G
T
E
Rhesus Macaque
Macaca mulatta
XP_001113470
483
53046
Y430
A
F
K
E
E
H
I
Y
P
T
I
I
G
T
E
Dog
Lupus familis
XP_852307
409
45618
Y351
A
F
K
E
Q
H
I
Y
P
T
I
I
S
T
E
Cat
Felis silvestris
Mouse
Mus musculus
Q9WU56
423
47484
Y370
A
F
K
E
Q
Y
I
Y
P
T
I
V
S
T
E
Rat
Rattus norvegicus
Q4KM92
423
47497
Y370
A
F
K
E
Q
Y
I
Y
P
T
I
V
S
T
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510884
469
53590
Y390
I
F
K
E
Q
Y
I
Y
S
T
I
I
K
T
E
Chicken
Gallus gallus
XP_415090
409
46045
Y354
V
F
K
E
Q
Y
I
Y
P
T
I
I
N
T
E
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001008603
376
42830
A322
T
E
Q
E
E
A
I
A
D
F
K
E
K
H
I
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_650899
410
47206
I358
Q
E
F
I
E
R
E
I
F
S
Q
I
Y
K
T
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001202324
494
54942
Y357
A
F
K
H
K
H
I
Y
P
N
I
I
V
R
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P53167
370
41857
N317
G
Y
N
T
K
L
R
N
L
L
Y
C
E
I
R
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.8
83
74.9
N.A.
84.5
84.7
N.A.
65.6
71.4
N.A.
56.6
N.A.
40.5
N.A.
N.A.
45.3
Protein Similarity:
100
99
84
80
N.A.
89.6
90.4
N.A.
75.4
81.9
N.A.
71.1
N.A.
58.5
N.A.
N.A.
59.1
P-Site Identity:
100
100
100
86.6
N.A.
73.3
73.3
N.A.
66.6
73.3
N.A.
20
N.A.
13.3
N.A.
N.A.
66.6
P-Site Similarity:
100
100
100
93.3
N.A.
93.3
93.3
N.A.
80
86.6
N.A.
26.6
N.A.
20
N.A.
N.A.
73.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
20.6
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
33.7
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
59
0
0
0
0
9
0
9
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
9
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
9
0
0
0
0
0
0
% D
% Glu:
0
17
0
75
42
0
9
0
0
0
0
9
9
0
75
% E
% Phe:
0
75
9
0
0
0
0
0
9
9
0
0
0
0
0
% F
% Gly:
9
0
0
0
0
0
0
0
0
0
0
0
25
0
0
% G
% His:
0
0
0
9
0
42
0
0
0
0
0
0
0
9
0
% H
% Ile:
9
0
0
9
0
0
84
9
0
0
75
67
0
9
9
% I
% Lys:
0
0
75
0
17
0
0
0
0
0
9
0
17
9
0
% K
% Leu:
0
0
0
0
0
9
0
0
9
9
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
9
0
0
0
0
9
0
9
0
0
9
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
67
0
0
0
0
0
0
% P
% Gln:
9
0
9
0
42
0
0
0
0
0
9
0
0
0
0
% Q
% Arg:
0
0
0
0
0
9
9
0
0
0
0
0
0
9
9
% R
% Ser:
0
0
0
0
0
0
0
0
9
9
0
0
25
0
0
% S
% Thr:
9
0
0
9
0
0
0
0
0
67
0
0
0
67
9
% T
% Val:
9
0
0
0
0
0
0
0
0
0
0
17
9
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
9
0
0
0
34
0
75
0
0
9
0
9
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _